Rapid spectral analysis for spectral imaging

Steven L. Jacques, Ravikant Samatham, Niloy Choudhury

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Spectral imaging requires rapid analysis of spectra associated with each pixel. A rapid algorithm has been developed that uses iterative matrix inversions to solve for the absorption spectra of a tissue using a lookup table for photon pathlength based on numerical simulations. The algorithm uses tissue water content as an internal standard to specify the strength of optical scattering. An experimental example is presented on the spectroscopy of portwine stain lesions. When implemented in MATLAB, the method is ~100-fold faster than using fminsearch().

Original languageEnglish (US)
Pages (from-to)157-164
Number of pages8
JournalBiomedical Optics Express
Volume1
Issue number1
DOIs
StatePublished - Aug 2 2010

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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    Jacques, S. L., Samatham, R., & Choudhury, N. (2010). Rapid spectral analysis for spectral imaging. Biomedical Optics Express, 1(1), 157-164. https://doi.org/10.1364/BOE.1.000157