Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig i acute HIV infection brief-communication

The RV411 study group

Research output: Contribution to journalArticlepeer-review

115 Scopus citations

Abstract

Antiretroviral therapy during the earliest stage of acute HIV infection (Fiebig I) might minimize establishment of a latent HIV reservoir and thereby facilitate viremic control after analytical treatment interruption. We show that 8 participants, who initiated treatment during Fiebig I and were treated for a median of 2.8 years, all experienced rapid viral load rebound following analytical treatment interruption, indicating that additional strategies are required to control or eradicate HIV.

Original languageEnglish (US)
Pages (from-to)923-926
Number of pages4
JournalNature medicine
Volume24
Issue number7
DOIs
StatePublished - Jul 1 2018
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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