Rapid and sensitive LC-MS approach to quantify non-radioactive transition metal impurities in metal radionuclides

Dexing Zeng, Carolyn J. Anderson

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A rapid and sensitive LC-MS approach for the quantification of non-radioactive metal contaminants present in metal radionuclide formulations was developed. Traditional 12C/1H and heavy stable isotope 13C/2H-labeled chelator-amino acid conjugates are used as chelating agents to quantify contaminating transition metals, allowing for determination of effective specific activity of radio-metals.

Original languageEnglish (US)
Pages (from-to)2697-2699
Number of pages3
JournalChemical Communications
Volume49
Issue number26
DOIs
StatePublished - Apr 4 2013
Externally publishedYes

Fingerprint

Radioisotopes
Transition metals
Metals
Impurities
Chelating Agents
Chelation
Isotopes
Amino acids
Amino Acids

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Rapid and sensitive LC-MS approach to quantify non-radioactive transition metal impurities in metal radionuclides. / Zeng, Dexing; Anderson, Carolyn J.

In: Chemical Communications, Vol. 49, No. 26, 04.04.2013, p. 2697-2699.

Research output: Contribution to journalArticle

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