Rapid acquisition of auditory brainstem responses with multiple frequency and intensity tone-bursts

Curtin Mitchell, J. Beth Kempton, Thomas Creedon, Dennis Trune

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Auditory brainstem response (ABR) thresholds, latency and amplitude functions were obtained in mice using stimuli presented singly and as a multiple stimulus sequence. All stimuli were tone-bursts at frequencies from 4 to 32 kHz. The multiple stimulus consisted of a sequence of 20 tone-bursts of four different frequencies at five intensities separated by 12 ms. A comparison of responses to stimuli presented singly and those obtained with the 20-stimulus train showed no significant difference in thresholds. Also, no differences were found in response latencies or amplitudes, indicating that the responses from multiple stimuli were not adapted or otherwise affected. The use of this 20-stimulus train can result in significant time savings for data acquisition compared with single stimuli. These findings demonstrate the feasibility of the rapid acquisition of unadapted cochlear and brainstem responses at different frequencies using a sequence of tone-bursts at different frequencies and intensities.

Original languageEnglish (US)
Pages (from-to)38-46
Number of pages9
JournalHearing Research
Volume99
Issue number1-2
DOIs
StatePublished - Sep 15 1996

Fingerprint

Brain Stem Auditory Evoked Potentials
Reaction Time
Cochlea
Brain Stem

Keywords

  • amplitude
  • auditory brainstem response
  • latency
  • multiple stimulus
  • threshold
  • tone-burst

ASJC Scopus subject areas

  • Sensory Systems

Cite this

Rapid acquisition of auditory brainstem responses with multiple frequency and intensity tone-bursts. / Mitchell, Curtin; Kempton, J. Beth; Creedon, Thomas; Trune, Dennis.

In: Hearing Research, Vol. 99, No. 1-2, 15.09.1996, p. 38-46.

Research output: Contribution to journalArticle

Mitchell, Curtin ; Kempton, J. Beth ; Creedon, Thomas ; Trune, Dennis. / Rapid acquisition of auditory brainstem responses with multiple frequency and intensity tone-bursts. In: Hearing Research. 1996 ; Vol. 99, No. 1-2. pp. 38-46.
@article{4b1de7f6a72349a7b4b38678b0d7a8fa,
title = "Rapid acquisition of auditory brainstem responses with multiple frequency and intensity tone-bursts",
abstract = "Auditory brainstem response (ABR) thresholds, latency and amplitude functions were obtained in mice using stimuli presented singly and as a multiple stimulus sequence. All stimuli were tone-bursts at frequencies from 4 to 32 kHz. The multiple stimulus consisted of a sequence of 20 tone-bursts of four different frequencies at five intensities separated by 12 ms. A comparison of responses to stimuli presented singly and those obtained with the 20-stimulus train showed no significant difference in thresholds. Also, no differences were found in response latencies or amplitudes, indicating that the responses from multiple stimuli were not adapted or otherwise affected. The use of this 20-stimulus train can result in significant time savings for data acquisition compared with single stimuli. These findings demonstrate the feasibility of the rapid acquisition of unadapted cochlear and brainstem responses at different frequencies using a sequence of tone-bursts at different frequencies and intensities.",
keywords = "amplitude, auditory brainstem response, latency, multiple stimulus, threshold, tone-burst",
author = "Curtin Mitchell and Kempton, {J. Beth} and Thomas Creedon and Dennis Trune",
year = "1996",
month = "9",
day = "15",
doi = "10.1016/S0378-5955(96)00081-0",
language = "English (US)",
volume = "99",
pages = "38--46",
journal = "Hearing Research",
issn = "0378-5955",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Rapid acquisition of auditory brainstem responses with multiple frequency and intensity tone-bursts

AU - Mitchell, Curtin

AU - Kempton, J. Beth

AU - Creedon, Thomas

AU - Trune, Dennis

PY - 1996/9/15

Y1 - 1996/9/15

N2 - Auditory brainstem response (ABR) thresholds, latency and amplitude functions were obtained in mice using stimuli presented singly and as a multiple stimulus sequence. All stimuli were tone-bursts at frequencies from 4 to 32 kHz. The multiple stimulus consisted of a sequence of 20 tone-bursts of four different frequencies at five intensities separated by 12 ms. A comparison of responses to stimuli presented singly and those obtained with the 20-stimulus train showed no significant difference in thresholds. Also, no differences were found in response latencies or amplitudes, indicating that the responses from multiple stimuli were not adapted or otherwise affected. The use of this 20-stimulus train can result in significant time savings for data acquisition compared with single stimuli. These findings demonstrate the feasibility of the rapid acquisition of unadapted cochlear and brainstem responses at different frequencies using a sequence of tone-bursts at different frequencies and intensities.

AB - Auditory brainstem response (ABR) thresholds, latency and amplitude functions were obtained in mice using stimuli presented singly and as a multiple stimulus sequence. All stimuli were tone-bursts at frequencies from 4 to 32 kHz. The multiple stimulus consisted of a sequence of 20 tone-bursts of four different frequencies at five intensities separated by 12 ms. A comparison of responses to stimuli presented singly and those obtained with the 20-stimulus train showed no significant difference in thresholds. Also, no differences were found in response latencies or amplitudes, indicating that the responses from multiple stimuli were not adapted or otherwise affected. The use of this 20-stimulus train can result in significant time savings for data acquisition compared with single stimuli. These findings demonstrate the feasibility of the rapid acquisition of unadapted cochlear and brainstem responses at different frequencies using a sequence of tone-bursts at different frequencies and intensities.

KW - amplitude

KW - auditory brainstem response

KW - latency

KW - multiple stimulus

KW - threshold

KW - tone-burst

UR - http://www.scopus.com/inward/record.url?scp=0030587110&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030587110&partnerID=8YFLogxK

U2 - 10.1016/S0378-5955(96)00081-0

DO - 10.1016/S0378-5955(96)00081-0

M3 - Article

C2 - 8970812

AN - SCOPUS:0030587110

VL - 99

SP - 38

EP - 46

JO - Hearing Research

JF - Hearing Research

SN - 0378-5955

IS - 1-2

ER -