Randomized controlled trials of psychological therapies for management of chronic pain in children and adolescents: An updated meta-analytic review

Tonya M. Palermo, Christopher Eccleston, Amy Holley, Amanda C de C Williams, Stephen Morley

Research output: Contribution to journalArticle

249 Citations (Scopus)

Abstract

The purpose of this meta-analytic review was to quantify the effects of psychological therapies for the management of chronic pain in youth. Specifically, in this review we updated previous systematic reviews of randomized controlled trials by including new trials, and by adding disability and emotional functioning to pain as treatment outcomes. Electronic searches of the Cochrane Register of Randomised Controlled Trials, MEDLINE, PsycLIT, EMBASE, and the Social Sciences Citation Index were conducted from inception through August 2008. Methodological quality of the studies was assessed, and data extracted on the three primary outcomes of interest. Twenty-five trials including 1247 young people met inclusion criteria and were included in the meta-analysis. Meta-analytic findings demonstrated a large positive effect of psychological intervention on pain reduction at immediate post-treatment and follow-up in youth with headache, abdominal pain, and fibromyalgia. Small and non-significant effects were found for improvements in disability and emotional functioning, although there were limited data on these outcomes available in the included studies. Omnibus cognitive-behavioral therapy, relaxation therapy, and biofeedback all produced significant and positive effects on pain reduction. Studies directly comparing the effects of self-administered versus therapist-administered interventions found similar effects on pain reduction. Psychological therapies result in improvement in pain relief across several different pain conditions in children. Future trials are needed that incorporate non-pain outcome domains, that focus significant therapeutic content on reductions in disability, and that include extended follow-up to better understand maintenance of treatment effects.

Original languageEnglish (US)
Pages (from-to)387-397
Number of pages11
JournalPain
Volume148
Issue number3
DOIs
StatePublished - Mar 2010

Fingerprint

Chronic Pain
Randomized Controlled Trials
Psychology
Pain
Therapeutics
Relaxation Therapy
Fibromyalgia
Social Sciences
Cognitive Therapy
MEDLINE
Abdominal Pain
Headache
Meta-Analysis

Keywords

  • Children
  • Chronic pain
  • Meta-analysis
  • Pain
  • Psychological therapies
  • Randomized controlled trials
  • Systematic review

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine
  • Neurology
  • Pharmacology

Cite this

Randomized controlled trials of psychological therapies for management of chronic pain in children and adolescents : An updated meta-analytic review. / Palermo, Tonya M.; Eccleston, Christopher; Holley, Amy; Williams, Amanda C de C; Morley, Stephen.

In: Pain, Vol. 148, No. 3, 03.2010, p. 387-397.

Research output: Contribution to journalArticle

Palermo, Tonya M. ; Eccleston, Christopher ; Holley, Amy ; Williams, Amanda C de C ; Morley, Stephen. / Randomized controlled trials of psychological therapies for management of chronic pain in children and adolescents : An updated meta-analytic review. In: Pain. 2010 ; Vol. 148, No. 3. pp. 387-397.
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