Radionuclide detection of diffuse interstitial pulmonary calcification

G. M. Grames; Donald Sauser; C. Jansen; R. E. Soderblom; J. E. Hodgkin; M. S. Stilson

doi:10.1001/jama.230.7.992

Radionuclide detection of diffuse interstitial pulmonary calcification

G. M. Grames, Donald Sauser, C. Jansen, R. E. Soderblom, J. E. Hodgkin, M. S. Stilson

Research output: Contribution to journal › Article › peer-review

Abstract

Two patients who had hypercalcemia, one from multiple myeloma and the other from metastatic carcinoma, showed striking concentrations of bone seeking radiopharmaceuticals in the lungs on routine bone scans. Neither patient had roentgenographic evidence of intrapulmonary calcification. Histologic examination in one patient show extensive interstitial pulmonary calcification. These cases illustrate the capability of radionuclides to detect interstitial pulmonary calcification when radiographic demonstration is lacking. The early detection of extraskeletal calcification by bone seeking radionuclides provides a unique opportunity, not previously available, to study metastatic calcification and the effects of treatment.

Original language	English (US)
Pages (from-to)	992-995
Number of pages	4
Journal	Journal of the American Medical Association
Volume	230
Issue number	7
DOIs	https://doi.org/10.1001/jama.230.7.992
State	Published - 1974
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1001/jama.230.7.992

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AU - Jansen, C.

AU - Soderblom, R. E.

AU - Hodgkin, J. E.

AU - Stilson, M. S.

PY - 1974

Y1 - 1974

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AB - Two patients who had hypercalcemia, one from multiple myeloma and the other from metastatic carcinoma, showed striking concentrations of bone seeking radiopharmaceuticals in the lungs on routine bone scans. Neither patient had roentgenographic evidence of intrapulmonary calcification. Histologic examination in one patient show extensive interstitial pulmonary calcification. These cases illustrate the capability of radionuclides to detect interstitial pulmonary calcification when radiographic demonstration is lacking. The early detection of extraskeletal calcification by bone seeking radionuclides provides a unique opportunity, not previously available, to study metastatic calcification and the effects of treatment.

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Radionuclide detection of diffuse interstitial pulmonary calcification

Abstract

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