Racial differences in the use of extracorporeal photopheresis for mycosis fungoides

Crystal Agi, Diane Kuhn, Jina Chung, John Zampella, Ginette Hinds

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: Extracorporeal photopheresis (ECP) is an effective treatment option for mycosis fungoides (MF) and associated with few systemic side effects. Objective: We sought to investigate whether there were differences in rates of ECP use between African-American and Caucasian patients with stage III/IV MF. Methods: We conducted a retrospective review of all patients treated for MF at the Johns Hopkins Hospital main campus outpatient clinic between 1999 and 2011. Results: We identified 65 patients with stage III or IV disease, 20 African-American and 45 Caucasian. Only 7 of 20 African-American patients (35%) compared with 30 of 45 (66%) of Caucasian patients were treated with ECP (p-=-0.029). In addition, ECP was discussed as an option for 45% of African-Americans compared to 82% of Caucasians (p-=-0.007). When discussed as an option, African-Americans and Caucasians had identical rates of ECP use (78% vs 81%, p-=-0.841). Conclusions: Differences in rates of ECP use exist among African-American patients when compared to their Caucasian counterparts and may be related to how often ECP is offered as a treatment option. Improving physician awareness of the factors that influence treatment decision making may help diminish discrepancies in treatment regimens among patients with MF.

Original languageEnglish (US)
Pages (from-to)266-268
Number of pages3
JournalJournal of Dermatological Treatment
Volume26
Issue number3
DOIs
StatePublished - Jun 1 2015
Externally publishedYes

Keywords

  • Cutaneous T-cell lymphoma
  • ECP
  • Ethnic skin
  • Mycosis fungoides

ASJC Scopus subject areas

  • Dermatology

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