Race/ethnic differences in bone mineral densities in older men

H. S. Nam, M. H. Shin, J. M. Zmuda, P. C. Leung, E. Barrett-Connor, Eric Orwoll, J. A. Cauley

Research output: Contribution to journalArticle

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Abstract

BMD was compared across race/ethnic groups. There were substantial race/ethnic differences in BMD even within African or Asian origin. Additional adjustment for body size greatly attenuated or reversed the differences between US Caucasian men vs Asian men. It illustrates the role of body size on the difference between these groups. Introduction: There is insufficient epidemiologic information about men's bone mineral density (BMD) levels across race/ethnic groups and geographic locations. Methods: In a cross-sectional design, we compared BMD in older men across seven race/ethnic groups in four countries. Femoral neck, total hip, and lumbar spine BMD were measured in men (age 65 to 78 years) from the Osteoporotic Fractures in Men (MrOS) Study (4,074 Caucasian, 208 African-American, 157 Asian, and 116 Hispanic men in USA), Tobago Bone Health Study (422 Afro-Caribbean men), MrOS Hong Kong Study (1,747 Hong Kong Chinese men), and the Namwon Study (1,079 South Korean men). BMD was corrected according to the cross-site calibration results for all scanners. Results: When compared with US Caucasian men, Afro-Caribbean and African-American men had, respectively, 8-20% and 6-11% higher age-adjusted mean BMD at all three bone sites. Hip BMD was similar in US Caucasian and Hispanic men, US Asian, Hong Kong Chinese, and Korean men had 3-14% lower BMD at all bone sites except femoral neck in Korean men. Additional adjustment for weight and height greatly attenuated or reversed the differences between US Caucasian men vs Asian men including US Asian, Hong Kong Chinese, and South Korean men. Among Asian groups, Korean men had higher femoral neck BMD and lower total hip BMD. Conclusion: These findings show substantial race/ethnic differences in BMD even within African or Asian origin and illustrate the important role of body size on the difference between Asian men and others.

Original languageEnglish (US)
Pages (from-to)2115-2123
Number of pages9
JournalOsteoporosis International
Volume21
Issue number12
DOIs
StatePublished - Dec 2010

Fingerprint

Bone Density
Hong Kong
Femur Neck
Body Size
Ethnic Groups
Pelvic Bones
Hispanic Americans
Bone and Bones
African Americans
Trinidad and Tobago
Geographic Locations
Osteoporotic Fractures

Keywords

  • Body size
  • Bone densitometry
  • Bone mineral density
  • Epidemiology
  • Men
  • Race/ethnicity

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

Cite this

Nam, H. S., Shin, M. H., Zmuda, J. M., Leung, P. C., Barrett-Connor, E., Orwoll, E., & Cauley, J. A. (2010). Race/ethnic differences in bone mineral densities in older men. Osteoporosis International, 21(12), 2115-2123. https://doi.org/10.1007/s00198-010-1188-3

Race/ethnic differences in bone mineral densities in older men. / Nam, H. S.; Shin, M. H.; Zmuda, J. M.; Leung, P. C.; Barrett-Connor, E.; Orwoll, Eric; Cauley, J. A.

In: Osteoporosis International, Vol. 21, No. 12, 12.2010, p. 2115-2123.

Research output: Contribution to journalArticle

Nam, HS, Shin, MH, Zmuda, JM, Leung, PC, Barrett-Connor, E, Orwoll, E & Cauley, JA 2010, 'Race/ethnic differences in bone mineral densities in older men', Osteoporosis International, vol. 21, no. 12, pp. 2115-2123. https://doi.org/10.1007/s00198-010-1188-3
Nam, H. S. ; Shin, M. H. ; Zmuda, J. M. ; Leung, P. C. ; Barrett-Connor, E. ; Orwoll, Eric ; Cauley, J. A. / Race/ethnic differences in bone mineral densities in older men. In: Osteoporosis International. 2010 ; Vol. 21, No. 12. pp. 2115-2123.
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