TY - JOUR
T1 - Quantitative evaluation of retinal artery occlusion using optical coherence tomography angiography
T2 - A case report
AU - Wang, Xiaogang
AU - Sun, Bin
AU - Wang, Jie
AU - Jia, Yali
AU - Huang, David
AU - Dong, Jing
N1 - Funding Information:
Funding: This work was supported by the National Natural Science Foundation of China under Grant No. 81501544, National Institutes of Health Grants R01 EY023285, DP3 DK104397, R01 EY024544, P30 EY010572, and an unrestricted grant from Research to Prevent Blindness to Casey Eye Institute, Oregon Health & Science University (OHSU).
Publisher Copyright:
Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Rationale: Retinal artery occlusion (RAO) results in painless, catastrophic vision loss in a period of seconds. Optical coherence tomography angiography (OCTA) can image retinal microcirculation, which is helpful to evaluate treatment response during the follow-up period. Using a single case with central RAO, we report its retinal perfusion changes before and after treatment using OCTA. Patient concerns: A 36-year-old Chinese man came to our clinic with a sudden, painless loss of vision (hand motion) in his left eye. A vasodilator (nicotinic acid) was used as the primary treatment. OCTA imaging and a visual field examination were performed to assess the retinal perfusion changes before and after treatment. Diagnosis: Retinal artery occlusion was considered. Interventions: This patient was treated with an inhaled oxygen-carbon dioxide mixture, nicotinic acid tablets (100 mg) taken orally twice a day, and intravenous infusion of nicotinic acid injections (60 mg) combined with 0.9% sodium chloride injections (100 ml) once a day for vasodilation. Outcomes: After treatment and 9 months of follow-up, the vessel density of the left eye at the 9-month follow-up appointment was improved in all quadrants. Lessons: Retinal edema and retinal atrophy were observed at the RAO onset and several months later, respectively. However, macular perfusion gradually increased after treatment. The timely administration of a vasodilator and the presence of the cilioretinal artery play important roles in the prevention of profound vision loss.
AB - Rationale: Retinal artery occlusion (RAO) results in painless, catastrophic vision loss in a period of seconds. Optical coherence tomography angiography (OCTA) can image retinal microcirculation, which is helpful to evaluate treatment response during the follow-up period. Using a single case with central RAO, we report its retinal perfusion changes before and after treatment using OCTA. Patient concerns: A 36-year-old Chinese man came to our clinic with a sudden, painless loss of vision (hand motion) in his left eye. A vasodilator (nicotinic acid) was used as the primary treatment. OCTA imaging and a visual field examination were performed to assess the retinal perfusion changes before and after treatment. Diagnosis: Retinal artery occlusion was considered. Interventions: This patient was treated with an inhaled oxygen-carbon dioxide mixture, nicotinic acid tablets (100 mg) taken orally twice a day, and intravenous infusion of nicotinic acid injections (60 mg) combined with 0.9% sodium chloride injections (100 ml) once a day for vasodilation. Outcomes: After treatment and 9 months of follow-up, the vessel density of the left eye at the 9-month follow-up appointment was improved in all quadrants. Lessons: Retinal edema and retinal atrophy were observed at the RAO onset and several months later, respectively. However, macular perfusion gradually increased after treatment. The timely administration of a vasodilator and the presence of the cilioretinal artery play important roles in the prevention of profound vision loss.
KW - Case report
KW - Optical coherence tomography angiography
KW - Retinal artery occlusion
UR - http://www.scopus.com/inward/record.url?scp=85054463883&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85054463883&partnerID=8YFLogxK
U2 - 10.1097/MD.0000000000012652
DO - 10.1097/MD.0000000000012652
M3 - Article
C2 - 30290644
AN - SCOPUS:85054463883
VL - 97
JO - Medicine; analytical reviews of general medicine, neurology, psychiatry, dermatology, and pediatries
JF - Medicine; analytical reviews of general medicine, neurology, psychiatry, dermatology, and pediatries
SN - 0025-7974
IS - 40
M1 - e12652
ER -