Quantitative evaluation of retinal artery occlusion using optical coherence tomography angiography

A case report

Xiaogang Wang, Bin Sun, Jie Wang, Jia Yali, David Huang, Jing Dong

Research output: Contribution to journalArticle

Abstract

RATIONALE: Retinal artery occlusion (RAO) results in painless, catastrophic vision loss in a period of seconds. Optical coherence tomography angiography (OCTA) can image retinal microcirculation, which is helpful to evaluate treatment response during the follow-up period. Using a single case with central RAO, we report its retinal perfusion changes before and after treatment using OCTA.

PATIENT CONCERNS: A 36-year-old Chinese man came to our clinic with a sudden, painless loss of vision (hand motion) in his left eye. A vasodilator (nicotinic acid) was used as the primary treatment. OCTA imaging and a visual field examination were performed to assess the retinal perfusion changes before and after treatment.

DIAGNOSIS: Retinal artery occlusion was considered.

INTERVENTIONS: This patient was treated with an inhaled oxygen-carbon dioxide mixture, nicotinic acid tablets (100 mg) taken orally twice a day, and intravenous infusion of nicotinic acid injections (60 mg) combined with 0.9% sodium chloride injections (100 ml) once a day for vasodilation.

OUTCOMES: After treatment and 9 months of follow-up, the vessel density of the left eye at the 9-month follow-up appointment was improved in all quadrants.

LESSONS: Retinal edema and retinal atrophy were observed at the RAO onset and several months later, respectively. However, macular perfusion gradually increased after treatment. The timely administration of a vasodilator and the presence of the cilioretinal artery play important roles in the prevention of profound vision loss.

Original languageEnglish (US)
Pages (from-to)e12652
JournalMedicine
Volume97
Issue number40
DOIs
StatePublished - Oct 1 2018

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Retinal Artery Occlusion
Optical Coherence Tomography
Angiography
Niacin
Perfusion
Vasodilator Agents
Therapeutics
Papilledema
Injections
Microcirculation
Visual Fields
Intravenous Infusions
Vasodilation
Carbon Dioxide
Sodium Chloride
Tablets
Atrophy
Appointments and Schedules
Hand
Arteries

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Quantitative evaluation of retinal artery occlusion using optical coherence tomography angiography : A case report. / Wang, Xiaogang; Sun, Bin; Wang, Jie; Yali, Jia; Huang, David; Dong, Jing.

In: Medicine, Vol. 97, No. 40, 01.10.2018, p. e12652.

Research output: Contribution to journalArticle

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