Quantitative biliary dynamics: introduction of a new noninvasive scintigraphic technique

G. T. Krishnamurthy, V. R. Bobba, Donald McConnell, F. Turner, M. Mesgarzadeh, E. Kingston

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

We used a Tc-99m-labeled hepatobiliary agent to measure the partition of hepatic bile between gallbladder and intestine in sixteen normal patients and nine patients with cholelithiasis. In normal subjects, the fractions of the hepatic bile that flow into the gallbladder and the small intestine were widely variable, with mean values of 69 ± 7% (s.e.) and 31 ±7% respectively. Bile reflux into the common hepatic duct was rare, occurring during the first 2/3 of the gallblader ejection period and only when the ejection fraction was greater than 59%. The gallbladder's mean latent period, ejection period, ejection fraction, and ejection rate were 2 ± 1 min, 11 ± 1min, 59 ±4%, and 5.9%/min respectively. In patients with cholelithiasis, the fraction of hepatic bile flowing into the gallbladder was normal, but the ejection fraction was significantly reduced (p

Original languageEnglish (US)
Pages (from-to)217-223
Number of pages7
JournalJournal of Nuclear Medicine
Volume24
Issue number3
StatePublished - 1983
Externally publishedYes

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Gallbladder
Bile
Cholelithiasis
Liver
Bile Reflux
Common Hepatic Duct
Small Intestine
Intestines

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Krishnamurthy, G. T., Bobba, V. R., McConnell, D., Turner, F., Mesgarzadeh, M., & Kingston, E. (1983). Quantitative biliary dynamics: introduction of a new noninvasive scintigraphic technique. Journal of Nuclear Medicine, 24(3), 217-223.

Quantitative biliary dynamics : introduction of a new noninvasive scintigraphic technique. / Krishnamurthy, G. T.; Bobba, V. R.; McConnell, Donald; Turner, F.; Mesgarzadeh, M.; Kingston, E.

In: Journal of Nuclear Medicine, Vol. 24, No. 3, 1983, p. 217-223.

Research output: Contribution to journalArticle

Krishnamurthy, GT, Bobba, VR, McConnell, D, Turner, F, Mesgarzadeh, M & Kingston, E 1983, 'Quantitative biliary dynamics: introduction of a new noninvasive scintigraphic technique', Journal of Nuclear Medicine, vol. 24, no. 3, pp. 217-223.
Krishnamurthy GT, Bobba VR, McConnell D, Turner F, Mesgarzadeh M, Kingston E. Quantitative biliary dynamics: introduction of a new noninvasive scintigraphic technique. Journal of Nuclear Medicine. 1983;24(3):217-223.
Krishnamurthy, G. T. ; Bobba, V. R. ; McConnell, Donald ; Turner, F. ; Mesgarzadeh, M. ; Kingston, E. / Quantitative biliary dynamics : introduction of a new noninvasive scintigraphic technique. In: Journal of Nuclear Medicine. 1983 ; Vol. 24, No. 3. pp. 217-223.
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