Quantitation of pathogenic potential of Staphylococcus aureus

C. H. Zierdt, James Maclowry, E. A. Robertson

Research output: Contribution to journalArticle

Abstract

Numerical estimates of the pathogenicity of Staphyloccus aureus strains were made for phage-typed strains from a relative incidence of significant to nonsignificant isolates from hospital patients. For a specific phage-patterned strain, the number of isolates from significant (wounds, abscesses, blood, etc.) sites was divided by the number of isolates from nonsignificant (respiratory tract, body surfaces, etc.) sites. This value, multiplied by 100, was the index of infection potential (IIP), IIP values for the S. aureus strains studied ranged from a low of 8 to a high of 50. The average IIP for all phage-patterned strains that occurred 50 or more times was 20. There was an inverse relationship between length of the phage pattern (number of the 26 typing phages that lysed the strain) and pathogenicity. Those strains with shorter phage patterns had higher IIP values and were more pathogenic. Strains lysed by one phage had an average IIP of 27, whereas those lysed by 18 phages had an average IIP of 14.

Original languageEnglish (US)
Pages (from-to)700-703
Number of pages4
JournalJournal of Clinical Microbiology
Volume16
Issue number4
StatePublished - 1982
Externally publishedYes

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Bacteriophages
Staphylococcus aureus
Infection
Virulence
Bacteriophage Typing
Respiratory System
Abscess
Incidence
Wounds and Injuries

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Quantitation of pathogenic potential of Staphylococcus aureus. / Zierdt, C. H.; Maclowry, James; Robertson, E. A.

In: Journal of Clinical Microbiology, Vol. 16, No. 4, 1982, p. 700-703.

Research output: Contribution to journalArticle

Zierdt, C. H. ; Maclowry, James ; Robertson, E. A. / Quantitation of pathogenic potential of Staphylococcus aureus. In: Journal of Clinical Microbiology. 1982 ; Vol. 16, No. 4. pp. 700-703.
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