Quantification of Shunt Volume Through Ventricular Septal Defect by Real-Time 3-D Color Doppler Echocardiography

An in Vitro Study

Meihua Zhu, Muhammad Ashraf, Lydia Tam, Cole Streiff, Sumito Kimura, Eriko Shimada, David Sahn

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Quantification of shunt volume is important for ventricular septal defects (VSDs). The aim of the in vitro study described here was to test the feasibility of using real-time 3-D color Doppler echocardiography (RT3-D-CDE) to quantify shunt volume through a modeled VSD. Eight porcine heart phantoms with VSDs ranging in diameter from 3 to 25 mm were studied. Each phantom was passively driven at five different stroke volumes from 30 to 70 mL and two stroke rates, 60 and 120 strokes/min. RT3-D-CDE full volumes were obtained at color Doppler volume rates of 15, 20 and 27 volumes/s. Shunt flow derived from RT3-D-CDE was linearly correlated with pump-driven stroke volume (R = 0.982). RT3-D-CDE-derived shunt volumes from three color Doppler flow rate settings and two stroke rate acquisitions did not differ (p > 0.05). The use of RT3-D-CDE to determine shunt volume though VSDs is feasible. Different color volume rates/heart rates under clinically/physiologically relevant range have no effect on VSD 3-D shunt volume determination.

Original languageEnglish (US)
JournalUltrasound in Medicine and Biology
DOIs
StateAccepted/In press - Apr 28 2015

Fingerprint

Doppler Color Echocardiography
echocardiography
Ventricular Heart Septal Defects
shunts
color
defects
Color
Stroke
Stroke Volume
stroke volume
strokes
Swine
Heart Rate
In Vitro Techniques
heart rate
acquisition
flow velocity
pumps

Keywords

  • Real-time 3-D color Doppler echocardiography
  • Shunt volume
  • Ventricular septal defect

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Biophysics

Cite this

Quantification of Shunt Volume Through Ventricular Septal Defect by Real-Time 3-D Color Doppler Echocardiography : An in Vitro Study. / Zhu, Meihua; Ashraf, Muhammad; Tam, Lydia; Streiff, Cole; Kimura, Sumito; Shimada, Eriko; Sahn, David.

In: Ultrasound in Medicine and Biology, 28.04.2015.

Research output: Contribution to journalArticle

Zhu, Meihua ; Ashraf, Muhammad ; Tam, Lydia ; Streiff, Cole ; Kimura, Sumito ; Shimada, Eriko ; Sahn, David. / Quantification of Shunt Volume Through Ventricular Septal Defect by Real-Time 3-D Color Doppler Echocardiography : An in Vitro Study. In: Ultrasound in Medicine and Biology. 2015.
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