Quality of life measures in soft tissue sarcoma

Kenneth R. Gundle, Amy M. Cizik, Robin L. Jones, Darin J. Davidson

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


The assessment of health-related quality of life (HRQL) via patient-reported outcomes has the potential to answer critical questions and improve the care of soft tissue sarcoma (STS). This review outlines the rationale for quality of life measures in sarcoma, and details various instrument types: disease- and anatomic-specific, provider-generated, generic HRQL and health state utilities. Prior usage in STS populations, relative advantages of specific patient-reported outcome measures and a framework for selecting appropriate measures are discussed. Uniform incorporation of validated HRQL measures in STS clinical research would further the understanding of patient wellbeing beyond traditional clinical measures, and more widespread use of health state utilities measures in particular has the potential to facilitate comparative effectiveness research.

Original languageEnglish (US)
Pages (from-to)95-100
Number of pages6
JournalExpert review of anticancer therapy
Issue number1
StatePublished - Jan 1 2014
Externally publishedYes


  • clinical research
  • health state utilities
  • health-related quality of life
  • patient-reported outcomes
  • soft tissue sarcoma

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)


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