Quality of HIV Care and Mortality Rates in HIV-Infected Patients

Philip Todd Korthuis, Kathleen A. McGinnis, Kevin L. Kraemer, Adam J. Gordon, Melissa Skanderson, Amy C. Justice, Stephen Crystal, Matthew Bidwell Goetz, Cynthia L. Gibert, David Rimland, Lynn E. Fiellin, Julie R. Gaither, Karen Wang, Steven M. Asch, Donald Keith McInnes, Michael E. Ohl, Kendall Bryant, Janet P. Tate, Mona Duggal, David A. Fiellin

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Background. The Patient Protection and Affordable Care Act encourages healthcare systems to track quality-of-care measures; little is known about their impact on mortality rates. The objective of this study was to assess associations between HIV quality of care and mortality rates. Methods. A longitudinal survival analysis of the Veterans Aging Cohort Study included 3038 human immunodeficiency virus (HIV)-infected patients enrolled between June 2002 and July 2008. The independent variable was receipt of ≥80% of 9 HIV quality indicators (QIs) abstracted from medical records in the 12 months after enrollment. Overall mortality rates through 2014 were assessed from the Veterans Health Administration, Medicare, and Social Security National Death Index records. We assessed associations between receiving ≥80% of HIV QIs and mortality rates using Kaplan-Meier survival analysis and adjusted Cox proportional hazards models. Results were stratified by unhealthy alcohol and illicit drug use. Results. The majority of participants were male (97.5%) and black (66.8%), with a mean (standard deviation) age of 49.0 (8.8) years. Overall, 25.9% reported past-year unhealthy alcohol use and 28.4% reported past-year illicit drug use. During 24 805 person-years of follow-up (mean [standard deviation], 8.2 [3.3] years), those who received ≥80% of QIs experienced lower age-adjusted mortality rates (adjusted hazard ratio, 0.75; 95% confidence interval,. 65-.86). Adjustment for disease severity attenuated the association. Conclusions. Receipt of ≥80% of select HIV QIs is associated with improved survival in a sample of predominantly male, black, HIV-infected patients but was insufficient to overcome adjustment for disease severity. Interventions to ensure high-quality care and address underlying chronic illness may improve survival in HIV-infected patients.

Original languageEnglish (US)
Pages (from-to)233-239
Number of pages7
JournalClinical Infectious Diseases
Issue number2
StatePublished - Jan 15 2016


  • HIV
  • alcohol
  • health care
  • opioid-related disorders
  • quality of health care

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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