TY - JOUR
T1 - Psychiatric and substance use disorders comorbidities in veterans with hepatitis C virus and HIV coinfection
AU - Fuller, Bret E.
AU - Loftis, Jennifer M.
AU - Rodriguez, Veronica L.
AU - McQuesten, Matthew J.
AU - Hauser, Peter
PY - 2009/7
Y1 - 2009/7
N2 - PURPOSE OF REVIEW: A growing number of veterans in theVeterans Health Administration are coinfected with HIV and hepatitis C virus. This review covers timely research relative to comorbid conditions that are common in this population including psychiatric diagnoses, substance use disorders and neurocognitive problems. RECENT FINDINGS: Current literature on the psychiatric, substance use disorders and cognitive problems of the coinfected population show that not only are rates of morbidity higher in the coinfected population but that this affects antiviral treatments as well. There is new evidence that brain injuries and infiltration of the virus into the central nervous system may be responsible for cognitive dysfunction. Cotesting, particularly in hepatitis C infected individuals, is not done routinely despite shared risk factors. SUMMARY: With this understanding of the comorbidities of the coinfected population, integrated healthcare models involving mental health, internal medicine, substance abuse treatment and internal medicine are crucial to work with these medically and psychologically complex patients.
AB - PURPOSE OF REVIEW: A growing number of veterans in theVeterans Health Administration are coinfected with HIV and hepatitis C virus. This review covers timely research relative to comorbid conditions that are common in this population including psychiatric diagnoses, substance use disorders and neurocognitive problems. RECENT FINDINGS: Current literature on the psychiatric, substance use disorders and cognitive problems of the coinfected population show that not only are rates of morbidity higher in the coinfected population but that this affects antiviral treatments as well. There is new evidence that brain injuries and infiltration of the virus into the central nervous system may be responsible for cognitive dysfunction. Cotesting, particularly in hepatitis C infected individuals, is not done routinely despite shared risk factors. SUMMARY: With this understanding of the comorbidities of the coinfected population, integrated healthcare models involving mental health, internal medicine, substance abuse treatment and internal medicine are crucial to work with these medically and psychologically complex patients.
KW - Coinfection
KW - HIV
KW - Hepatitis C virus
UR - http://www.scopus.com/inward/record.url?scp=67651011588&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67651011588&partnerID=8YFLogxK
U2 - 10.1097/YCO.0b013e32832cadb9
DO - 10.1097/YCO.0b013e32832cadb9
M3 - Review article
C2 - 19436202
AN - SCOPUS:67651011588
SN - 0951-7367
VL - 22
SP - 401
EP - 408
JO - Current Opinion in Psychiatry
JF - Current Opinion in Psychiatry
IS - 4
ER -