Psoralen increases melatonin levels without ultraviolet light

L. J. Grota, Alfred Lewy, L. A. Goldsmith, G. M. Brown

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We examined the serum melatonin response to 8-MOP in intact and pinealectomized male rats. In 8-MOP treated animals, both intact and pinealectomized animals have increased serum melatonin (RIA) levels relative to vehicle controls, but the increase is greater in intact than in pinealectomize animals. These data indicate that increased serum melatonin levels following 8-MOP injection are the results of increased melatonin secretion from the pineal gland. The data also suggest that part of the serum melatonin increase may be from a yet unidentified tissue.

Original languageEnglish (US)
Pages (from-to)385-387
Number of pages3
JournalAnnals of the New York Academy of Sciences
VolumeVOL. 453
StatePublished - 1985
Externally publishedYes

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Ficusin
Melatonin
Ultraviolet Rays
Methoxsalen
Animals
Serum
Pineal Gland
Rats
Tissue
Injections

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Grota, L. J., Lewy, A., Goldsmith, L. A., & Brown, G. M. (1985). Psoralen increases melatonin levels without ultraviolet light. Annals of the New York Academy of Sciences, VOL. 453, 385-387.

Psoralen increases melatonin levels without ultraviolet light. / Grota, L. J.; Lewy, Alfred; Goldsmith, L. A.; Brown, G. M.

In: Annals of the New York Academy of Sciences, Vol. VOL. 453, 1985, p. 385-387.

Research output: Contribution to journalArticle

Grota, LJ, Lewy, A, Goldsmith, LA & Brown, GM 1985, 'Psoralen increases melatonin levels without ultraviolet light', Annals of the New York Academy of Sciences, vol. VOL. 453, pp. 385-387.
Grota, L. J. ; Lewy, Alfred ; Goldsmith, L. A. ; Brown, G. M. / Psoralen increases melatonin levels without ultraviolet light. In: Annals of the New York Academy of Sciences. 1985 ; Vol. VOL. 453. pp. 385-387.
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