Pseudogout of the cervical and thoracic spine mimicking infection after lumbar fusion

Case report

Kelly J. Bridges, Carli L. Bullis, Ajay Wanchu, Khoi Than

Research output: Contribution to journalArticle

Abstract

Pseudogout is a form of acute calcium pyrophosphate deposition (CPPD) disease that typically afflicts the elderly. CPPD commonly involves larger joints, such as the knees, wrists, shoulders, and hips, and has been known to involve the spine. The authors report the case of a 66-year-old woman with a recent history of lumbar laminectomy and fusion who presented 5 weeks postprocedure with a clinical and radiographic picture consistent with multilevel skip lesions involving the cervical and thoracic spine, thoracic discitis, and epidural abscess. Serial blood cultures and repeat biopsy samples were sterile. Subsequent wrist and ankle erythema, pain, and swelling led to synovial fluid analysis, and pseudogout was diagnosed. She was treated with an interleukin-1 inhibitor with immediate symptom relief. To the authors' knowledge, this is only the second report of spinal pseudogout presenting with a clinical and radiographic picture consistent with discitis and epidural abscess. This report is the first to report skip lesions of pseudogout occurring throughout the spine that are uniquely remote from a recent lumbar surgery.

Original languageEnglish (US)
Pages (from-to)145-149
Number of pages5
JournalJournal of Neurosurgery: Spine
Volume27
Issue number2
DOIs
StatePublished - Aug 1 2017

Fingerprint

Chondrocalcinosis
Spine
Thorax
Epidural Abscess
Discitis
Infection
Wrist
Calcium Pyrophosphate
Laminectomy
Synovial Fluid
Erythema
Interleukin-1
Ankle
Hip
Knee
Joints
Biopsy
Pain

Keywords

  • Calcium pyrophosphate deposition
  • Cervical
  • CPPD
  • Lumbar
  • Pseudogout
  • Thoracic

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pseudogout of the cervical and thoracic spine mimicking infection after lumbar fusion : Case report. / Bridges, Kelly J.; Bullis, Carli L.; Wanchu, Ajay; Than, Khoi.

In: Journal of Neurosurgery: Spine, Vol. 27, No. 2, 01.08.2017, p. 145-149.

Research output: Contribution to journalArticle

Bridges, Kelly J. ; Bullis, Carli L. ; Wanchu, Ajay ; Than, Khoi. / Pseudogout of the cervical and thoracic spine mimicking infection after lumbar fusion : Case report. In: Journal of Neurosurgery: Spine. 2017 ; Vol. 27, No. 2. pp. 145-149.
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