TY - JOUR
T1 - Proton-Beam Therapy
AU - Braunstein, Glenn D.
AU - Loriaux, D. Lynn
AU - Kjellberg, Raymond N.
AU - Kliman, Bernard
PY - 1971/2/11
Y1 - 1971/2/11
N2 - To the Editor: Dawson and Dingman, in a letter to this journal,1 reported that of nine patients receiving Bragg-peak heavy-particle irradiation to pituitary tumors, serious neurologic complications, including cranial-nerve palsy, chiasmatic injury, seizures and vertigo, developed in eight. Four of the eight patients with neurologic complications received prior conventional or high-voltage X-irradiation. A personal communication from Dawson and Dingman indicates that the longest interval between heavy-particle irradiation and the onset of neurologic deficit was 14 months. We have followed three similar patients, in all of whom neurologic complications developed. M.G., a 42-year-old woman with acromegaly since 1959, received 4500 R.
AB - To the Editor: Dawson and Dingman, in a letter to this journal,1 reported that of nine patients receiving Bragg-peak heavy-particle irradiation to pituitary tumors, serious neurologic complications, including cranial-nerve palsy, chiasmatic injury, seizures and vertigo, developed in eight. Four of the eight patients with neurologic complications received prior conventional or high-voltage X-irradiation. A personal communication from Dawson and Dingman indicates that the longest interval between heavy-particle irradiation and the onset of neurologic deficit was 14 months. We have followed three similar patients, in all of whom neurologic complications developed. M.G., a 42-year-old woman with acromegaly since 1959, received 4500 R.
UR - http://www.scopus.com/inward/record.url?scp=0015219285&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015219285&partnerID=8YFLogxK
U2 - 10.1056/NEJM197102112840615
DO - 10.1056/NEJM197102112840615
M3 - Letter
C2 - 5539462
AN - SCOPUS:0015219285
SN - 0028-4793
VL - 284
SP - 332
EP - 333
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 6
ER -