Proteinuria as a surrogate marker for renal outcome: Are we there yet?

Rupali S. Avasare; Jai Radhakrishnan

doi:10.1038/ki.2015.301

Proteinuria as a surrogate marker for renal outcome: Are we there yet?

Rupali S. Avasare, Jai Radhakrishnan

Research output: Contribution to journal › Comment/debate › peer-review

9 Scopus citations

Abstract

Observational studies in glomerular diseases suggest that proteinuria reduction translates to improved outcomes. Because of a dearth of high-quality studies supporting this association, proteinuria is not universally recognized as a surrogate end point. Barbour et al. report on the longitudinal measure of proteinuria that best predicts hard renal outcomes. Their finding that time-varying proteinuria is the most reliable proteinuria metric is a necessary step in establishing proteinuria as a surrogate end point.

Original language	English (US)
Pages (from-to)	1228-1230
Number of pages	3
Journal	Kidney International
Volume	88
Issue number	6
DOIs	https://doi.org/10.1038/ki.2015.301
State	Published - Dec 1 2015
Externally published	Yes

ASJC Scopus subject areas

Nephrology

Access to Document

10.1038/ki.2015.301

Cite this

@article{d485d527c465486b8163616a3d68b9d0,

title = "Proteinuria as a surrogate marker for renal outcome: Are we there yet?",

abstract = "Observational studies in glomerular diseases suggest that proteinuria reduction translates to improved outcomes. Because of a dearth of high-quality studies supporting this association, proteinuria is not universally recognized as a surrogate end point. Barbour et al. report on the longitudinal measure of proteinuria that best predicts hard renal outcomes. Their finding that time-varying proteinuria is the most reliable proteinuria metric is a necessary step in establishing proteinuria as a surrogate end point.",

author = "Avasare, {Rupali S.} and Jai Radhakrishnan",

year = "2015",

month = dec,

day = "1",

doi = "10.1038/ki.2015.301",

language = "English (US)",

volume = "88",

pages = "1228--1230",

journal = "Kidney International",

issn = "0085-2538",

publisher = "Nature Publishing Group",

number = "6",

}

TY - JOUR

T1 - Proteinuria as a surrogate marker for renal outcome

T2 - Are we there yet?

AU - Avasare, Rupali S.

AU - Radhakrishnan, Jai

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Observational studies in glomerular diseases suggest that proteinuria reduction translates to improved outcomes. Because of a dearth of high-quality studies supporting this association, proteinuria is not universally recognized as a surrogate end point. Barbour et al. report on the longitudinal measure of proteinuria that best predicts hard renal outcomes. Their finding that time-varying proteinuria is the most reliable proteinuria metric is a necessary step in establishing proteinuria as a surrogate end point.

AB - Observational studies in glomerular diseases suggest that proteinuria reduction translates to improved outcomes. Because of a dearth of high-quality studies supporting this association, proteinuria is not universally recognized as a surrogate end point. Barbour et al. report on the longitudinal measure of proteinuria that best predicts hard renal outcomes. Their finding that time-varying proteinuria is the most reliable proteinuria metric is a necessary step in establishing proteinuria as a surrogate end point.

UR - http://www.scopus.com/inward/record.url?scp=84949870925&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84949870925&partnerID=8YFLogxK

U2 - 10.1038/ki.2015.301

DO - 10.1038/ki.2015.301

M3 - Comment/debate

AN - SCOPUS:84949870925

SN - 0085-2538

VL - 88

SP - 1228

EP - 1230

JO - Kidney International

JF - Kidney International

IS - 6

ER -

Proteinuria as a surrogate marker for renal outcome: Are we there yet?

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this