Protein-losing enteropathy in systemic lupus erythematosus - Diagnosis and monitoring immunosuppressive therapy by alpha-1-antitrypsin clearance in stool

Kent G. Benner, Anthony Montanaro

Research output: Contribution to journalArticle

40 Scopus citations


Enteric protein loss resulting in profound hypoalbuminemia and anasarca is an uncommon manifestation of systemic lupus erythematosus and only rarely is the initial presentation of disease. A few patients with SLE and protein-losing enteropathy in the absence of increased central venous pressure or intestinal lymphangiectasia have been reported. We describe the utility alpha-1-antitrypsin clearance in stool for diagnosing and monitoring enteric protein loss during successful immunosuppressive drug therapy in a patient who presented with massive enteric protein loss as the initial manifestation of systemic lupus erythematosus.

Original languageEnglish (US)
Pages (from-to)132-135
Number of pages4
JournalDigestive diseases and sciences
Issue number1
StatePublished - Jan 1 1989



  • hypoalbuminemia
  • protein-losing enteropathy
  • systemic lupus erythematosus
  • α-1-antitrypsin clearance

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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