Active immunization of guinea pigs and rabbits with outer membrane proteins (OMP) isolated from Shigella flexneri 3a and Shigella sonnei phase I protected the animals against keratoconjunctivitis shigellosa induced with the homologous or heterologous strain. Protection was also achieved in rabbits after passive immunization with anti-OMP immune serum. Active immunization with lipopolysaccharide of S. flexneri 3a did not protect rabbits against keratoconjunctivitis shigellosa.
|Original language||English (US)|
|Number of pages||4|
|Journal||Infection and Immunity|
|State||Published - Jan 1 1980|
ASJC Scopus subject areas
- Infectious Diseases