TY - JOUR
T1 - Prostate volumes defined by magnetic resonance imaging and computerized tomographic scans for three-dimensional conformal radiotherapy
AU - Roach, Mack
AU - Faillace-Akazawa, Pamela
AU - Malfatti, Christine
AU - Holland, John
AU - Hricak, Hedvig
PY - 1996/7/15
Y1 - 1996/7/15
N2 - Purpose: To compare the prostate volumes defined on magnetic resonance imaging (MRI), and noncontrast computerized tomographic (CT) scans used for three-dimensional (3D) treatment planning. Methods and Materials: Ten patients were simulated for treatment using immobilization and a retrograde urethrogram. 3D images were used to compare prostate volumes defined by MRI (4-6 mm thick slices) and CT images (5 mm thick slices). Prostate volumes were calculated in cm3 using the Scanditronix 3D planning system. MRI/CT images were merged using bony anatomy to define the regions of discrepancy in prostate volumes. Results: The mean prostate volume was 32% larger (range - 5-63%) when defined by noncontrast CT compared to MRI. The areas of nonagreement tended to occur in four distinct regions of discrepancy: (a) the posterior portion of the prostate, (b) the posterior-inferior-apical portion of the prostate, (c) the apex due to disagreement between a urethrogram based definition and the location defined by MRI, (d) regions corresponding to the neurovascular bundle. Conclusion: There is a tendency to overestimate the prostate volume by noncontrast CT compared to MRI. Awareness of this tendency should allow us to be to more accurately define the prostate during 3-D treatment planning.
AB - Purpose: To compare the prostate volumes defined on magnetic resonance imaging (MRI), and noncontrast computerized tomographic (CT) scans used for three-dimensional (3D) treatment planning. Methods and Materials: Ten patients were simulated for treatment using immobilization and a retrograde urethrogram. 3D images were used to compare prostate volumes defined by MRI (4-6 mm thick slices) and CT images (5 mm thick slices). Prostate volumes were calculated in cm3 using the Scanditronix 3D planning system. MRI/CT images were merged using bony anatomy to define the regions of discrepancy in prostate volumes. Results: The mean prostate volume was 32% larger (range - 5-63%) when defined by noncontrast CT compared to MRI. The areas of nonagreement tended to occur in four distinct regions of discrepancy: (a) the posterior portion of the prostate, (b) the posterior-inferior-apical portion of the prostate, (c) the apex due to disagreement between a urethrogram based definition and the location defined by MRI, (d) regions corresponding to the neurovascular bundle. Conclusion: There is a tendency to overestimate the prostate volume by noncontrast CT compared to MRI. Awareness of this tendency should allow us to be to more accurately define the prostate during 3-D treatment planning.
KW - 3D Treatment planning
KW - CT
KW - MRI
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U2 - 10.1016/0360-3016(96)00232-5
DO - 10.1016/0360-3016(96)00232-5
M3 - Article
C2 - 8751410
AN - SCOPUS:0030586042
SN - 0360-3016
VL - 35
SP - 1011
EP - 1018
JO - International Journal of Radiation Oncology Biology Physics
JF - International Journal of Radiation Oncology Biology Physics
IS - 5
ER -