Prostate specific antigen and prostate cancer

Prostate cancer (PCa) is a disease with high incidence and prevalence. Early detection of PCa has been an area for research to decrease its morbidity and mortality. The discovery of prostate specific antigen (PSA) revolutionized screening of PCa, which was largely dependent on detection of prostatic acid phosphatase and digital rectal examination. Several leading organizations and cancer societies, based on present evidence, have published their recommendations for its use in detection and monitoring of PCa. There has been difference in opinions on its appropriate threshold value to recommend prostate biopsy and benefits on health outcomes due to its use in screening. This new book presents and discusses current research in the study of PCa and it's role in the screening of prostate cancer.