Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Apurva A. Bonde; Elena K. Korngold; Bryan R. Foster; Antonio C. Westphalen; David R. Pettersson; Megan L. Troxell; Jeffry P. Simko; Fergus V. Coakley

doi:10.1016/j.clinimag.2015.12.015

Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Apurva A. Bonde, Elena K. Korngold, Bryan R. Foster, Antonio C. Westphalen, David R. Pettersson, Megan L. Troxell, Jeffry P. Simko, Fergus V. Coakley

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

Original language	English (US)
Pages (from-to)	365-369
Number of pages	5
Journal	Clinical Imaging
Volume	40
Issue number	3
DOIs	https://doi.org/10.1016/j.clinimag.2015.12.015
State	Published - May 1 2016

Keywords

MR imaging
Pathology
Prostate cancer
Pseudocapsule

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2015.12.015

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title = "Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?",

abstract = "Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.",

keywords = "MR imaging, Pathology, Prostate cancer, Pseudocapsule",

author = "Bonde, {Apurva A.} and Korngold, {Elena K.} and Foster, {Bryan R.} and Westphalen, {Antonio C.} and Pettersson, {David R.} and Troxell, {Megan L.} and Simko, {Jeffry P.} and Coakley, {Fergus V.}",

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year = "2016",

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doi = "10.1016/j.clinimag.2015.12.015",

language = "English (US)",

volume = "40",

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T1 - Prostate cancer with a pseudocapsule at MR imaging

T2 - A marker of high grade and stage disease?

AU - Bonde, Apurva A.

AU - Korngold, Elena K.

AU - Foster, Bryan R.

AU - Westphalen, Antonio C.

AU - Pettersson, David R.

AU - Troxell, Megan L.

AU - Simko, Jeffry P.

AU - Coakley, Fergus V.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

AB - Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

KW - MR imaging

KW - Pathology

KW - Prostate cancer

KW - Pseudocapsule

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JO - Clinical Imaging

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Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Abstract

Keywords

ASJC Scopus subject areas

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