Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Apurva A. Bonde, Elena Korngold, Bryan Foster, Antonio C. Westphalen, David Pettersson, Megan Troxell, Jeffry P. Simko, Fergus Coakley

Research output: Contribution to journalArticle

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Abstract

Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

Original languageEnglish (US)
Pages (from-to)365-369
Number of pages5
JournalClinical Imaging
Volume40
Issue number3
DOIs
Publication statusPublished - May 1 2016

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Keywords

  • MR imaging
  • Pathology
  • Prostate cancer
  • Pseudocapsule

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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