Abstract
An important determinant in interpreting the results of colorectal polyp chemoprevention trials is the rate of polyps missed during colonoscopic examination. We prospectively examined 90 patients by tandem colonoscopy performed by two alternating examiners. In 69 (76.7%) patients, 221 neoplastic lesions were documented histologically. Of a total of 58 lesions detected in 31 patients, no neoplastic lesion greater than or equal to 10 mm in size was missed; 16% of diminutive (≤5 mm) neoplastic polyps and 12.3% of mediumsized (6-9 mm) neoplastic polyps were missed by the first examiner. We conclude that an experienced colonoscopist will miss about 15% of colorectal neoplastic polyps less than 10 mm in size in the setting of adequate bowel preparation. Large (≥10 mm) polyps were rarely missed, however, with the "miss" rate in our study equal to 0, with a 95% confidence limit of 4.64%.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1769-1772 |
| Number of pages | 4 |
| Journal | Journal of the National Cancer Institute |
| Volume | 82 |
| Issue number | 22 |
| State | Published - Nov 21 1990 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
- Statistics, Probability and Uncertainty
- Applied Mathematics
- Physiology (medical)
- Radiology Nuclear Medicine and imaging
Cite this
Prospective study of the frequency and size distribution of polyps missed by colonoscopy. / Hixson, L. J.; Fennerty, M (Brian); Sampliner, R. E.; McGee, D.; Garewal, H.
In: Journal of the National Cancer Institute, Vol. 82, No. 22, 21.11.1990, p. 1769-1772.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prospective study of the frequency and size distribution of polyps missed by colonoscopy
AU - Hixson, L. J.
AU - Fennerty, M (Brian)
AU - Sampliner, R. E.
AU - McGee, D.
AU - Garewal, H.
PY - 1990/11/21
Y1 - 1990/11/21
N2 - An important determinant in interpreting the results of colorectal polyp chemoprevention trials is the rate of polyps missed during colonoscopic examination. We prospectively examined 90 patients by tandem colonoscopy performed by two alternating examiners. In 69 (76.7%) patients, 221 neoplastic lesions were documented histologically. Of a total of 58 lesions detected in 31 patients, no neoplastic lesion greater than or equal to 10 mm in size was missed; 16% of diminutive (≤5 mm) neoplastic polyps and 12.3% of mediumsized (6-9 mm) neoplastic polyps were missed by the first examiner. We conclude that an experienced colonoscopist will miss about 15% of colorectal neoplastic polyps less than 10 mm in size in the setting of adequate bowel preparation. Large (≥10 mm) polyps were rarely missed, however, with the "miss" rate in our study equal to 0, with a 95% confidence limit of 4.64%.
AB - An important determinant in interpreting the results of colorectal polyp chemoprevention trials is the rate of polyps missed during colonoscopic examination. We prospectively examined 90 patients by tandem colonoscopy performed by two alternating examiners. In 69 (76.7%) patients, 221 neoplastic lesions were documented histologically. Of a total of 58 lesions detected in 31 patients, no neoplastic lesion greater than or equal to 10 mm in size was missed; 16% of diminutive (≤5 mm) neoplastic polyps and 12.3% of mediumsized (6-9 mm) neoplastic polyps were missed by the first examiner. We conclude that an experienced colonoscopist will miss about 15% of colorectal neoplastic polyps less than 10 mm in size in the setting of adequate bowel preparation. Large (≥10 mm) polyps were rarely missed, however, with the "miss" rate in our study equal to 0, with a 95% confidence limit of 4.64%.
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UR - http://www.scopus.com/inward/citedby.url?scp=0025610533&partnerID=8YFLogxK
M3 - Article
C2 - 2231773
AN - SCOPUS:0025610533
VL - 82
SP - 1769
EP - 1772
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
SN - 0027-8874
IS - 22
ER -