Proprioception and Motor Control in Parkinson's Disease

Jürgen Konczak, Daniel M. Corcos, Fay Horak, Howard Poizner, Mark Shapiro, Paul Tuite, Jens Volkmann, Matthias Maschke

Research output: Contribution to journalArticle

143 Scopus citations

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder that leads to a progressive decline in motor function. Growing evidence indicates that PD patients also experience an array of sensory problems that negatively impact motor function. This is especially true for proprioceptive deficits, which profoundly degrade motor performance. This review specifically address the relation between proprioception and motor impairments in PD. It is structured around 4 themes: (a) It examines whether the sensitivity of kinaesthetic perception, which is based on proprioceptive inputs, is actually altered in PD. (b) It discusses whether failed processes of proprioceptive-motor integration are central to the motor problems in PD. (c) It presents recent findings focusing on the link between the proprioception and the balance problems in PD. And (d) it discusses the current state of knowledge of how levodopa medication and deep brain stimulation affect proprioceptive and motor function in PD. The authors conclude that a failure to evaluate and to map proprioceptive information onto voluntary and reflexive motor commands is an integral part of the observed motor symptoms in PD.

Original languageEnglish (US)
Pages (from-to)543-552
Number of pages10
JournalJournal of motor behavior
Volume41
Issue number6
DOIs
StatePublished - Nov 6 2009

Keywords

  • Basal ganglia
  • Kinaesthesia
  • Movement disorder
  • Sensorimotor integration

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience

Fingerprint Dive into the research topics of 'Proprioception and Motor Control in Parkinson's Disease'. Together they form a unique fingerprint.

  • Cite this

    Konczak, J., Corcos, D. M., Horak, F., Poizner, H., Shapiro, M., Tuite, P., Volkmann, J., & Maschke, M. (2009). Proprioception and Motor Control in Parkinson's Disease. Journal of motor behavior, 41(6), 543-552. https://doi.org/10.3200/35-09-002