Propranolol for Thyroid Storm

Jeffrey J. Abrams; Jeffrey Sandler; Steven G. Dorfman; Stan Van Hofe; Robert L. Young; Thomas A. Bowdle; Sheldon Rubenfeld; Alan J. Garber; Margareta Eriksson; Peter O. Kohler

doi:10.1056/NEJM197705122961916

Propranolol for Thyroid Storm

Jeffrey J. Abrams, Jeffrey Sandler, Steven G. Dorfman, Stan Van Hofe, Robert L. Young, Thomas A. Bowdle, Sheldon Rubenfeld, Alan J. Garber, Margareta Eriksson, Peter O. Kohler

Research output: Contribution to journal › Letter › peer-review

5 Scopus citations

Abstract

To the Editor: Eriksson et al. (N Engl J Med 296:263, 1977) concluded that “propranolol does not prevent thyroid storm” on the basis of two recent cases that they reported. We believe this important conclusion cannot be derived from their case reports. The authors state, “In the two patients described below, thyroid storm developed on seemingly adequate propranolol therapy for thyrotoxicosis.” The word “seemingly” is the rub. Both patients were given 40 mg of propranolol four times a day — a modest dose, especially in the face of the rapid turnover of most drugs in thyrotoxicosis. Also, there is.

Original language	English (US)
Pages (from-to)	1120-1121
Number of pages	2
Journal	New England Journal of Medicine
Volume	296
Issue number	19
DOIs	https://doi.org/10.1056/NEJM197705122961916
State	Published - May 12 1977
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "Propranolol for Thyroid Storm",

abstract = "To the Editor: Eriksson et al. (N Engl J Med 296:263, 1977) concluded that “propranolol does not prevent thyroid storm” on the basis of two recent cases that they reported. We believe this important conclusion cannot be derived from their case reports. The authors state, “In the two patients described below, thyroid storm developed on seemingly adequate propranolol therapy for thyrotoxicosis.” The word “seemingly” is the rub. Both patients were given 40 mg of propranolol four times a day — a modest dose, especially in the face of the rapid turnover of most drugs in thyrotoxicosis. Also, there is.",

author = "Abrams, {Jeffrey J.} and Jeffrey Sandler and Dorfman, {Steven G.} and {Van Hofe}, Stan and Young, {Robert L.} and Bowdle, {Thomas A.} and Sheldon Rubenfeld and Garber, {Alan J.} and Margareta Eriksson and Kohler, {Peter O.}",

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T1 - Propranolol for Thyroid Storm

AU - Abrams, Jeffrey J.

AU - Sandler, Jeffrey

AU - Dorfman, Steven G.

AU - Van Hofe, Stan

AU - Young, Robert L.

AU - Bowdle, Thomas A.

AU - Rubenfeld, Sheldon

AU - Garber, Alan J.

AU - Eriksson, Margareta

AU - Kohler, Peter O.

PY - 1977/5/12

Y1 - 1977/5/12

N2 - To the Editor: Eriksson et al. (N Engl J Med 296:263, 1977) concluded that “propranolol does not prevent thyroid storm” on the basis of two recent cases that they reported. We believe this important conclusion cannot be derived from their case reports. The authors state, “In the two patients described below, thyroid storm developed on seemingly adequate propranolol therapy for thyrotoxicosis.” The word “seemingly” is the rub. Both patients were given 40 mg of propranolol four times a day — a modest dose, especially in the face of the rapid turnover of most drugs in thyrotoxicosis. Also, there is.

AB - To the Editor: Eriksson et al. (N Engl J Med 296:263, 1977) concluded that “propranolol does not prevent thyroid storm” on the basis of two recent cases that they reported. We believe this important conclusion cannot be derived from their case reports. The authors state, “In the two patients described below, thyroid storm developed on seemingly adequate propranolol therapy for thyrotoxicosis.” The word “seemingly” is the rub. Both patients were given 40 mg of propranolol four times a day — a modest dose, especially in the face of the rapid turnover of most drugs in thyrotoxicosis. Also, there is.

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DO - 10.1056/NEJM197705122961916

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Propranolol for Thyroid Storm

Abstract

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