Prophylactic pacemaker use to allow β-blocker therapy in patients with chronic heart failure with bradycardia

Eric Stecker, A. Mark Fendrick, Bradley P. Knight, Keith D. Aaronson

Research output: Contribution to journalArticle

11 Scopus citations


Background: Although the benefits of β-blocker therapy for patients with congestive heart failure (CHF) are independent of pretreatment heart rate, patients with chronic systolic heart failure and low resting heart rates are often excluded from β-blocker therapy. We investigated the effectiveness and cost-effectiveness of prophylactic pacemaker insertion to facilitate β-blocker use in these patients. Methods: A Markov model simulated the natural history of a cohort of clinically stable patients with CHF (ejection fraction ≤35%, mean age 60 years) with resting heart rates of

Original languageEnglish (US)
Pages (from-to)820-828
Number of pages9
JournalAmerican Heart Journal
Issue number4
StatePublished - Apr 2006
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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