Prolonged use of extracorporeal membrane oxygenation as a rescue modality following traumatic brain injury

Jonathan A. Messing; Ritesh V. Agnihothri; Rachel Van Dusen; Farzad Najam; James R. Dunne; Jacqueline R. Honig; Babak Sarani

doi:10.1097/MAT.0000000000000103

Prolonged use of extracorporeal membrane oxygenation as a rescue modality following traumatic brain injury

Jonathan A. Messing, Ritesh V. Agnihothri, Rachel Van Dusen, Farzad Najam, James R. Dunne, Jacqueline R. Honig, Babak Sarani

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A 21-year-old male trauma patient presented after a motor vehicle crash, witnessed massive aspiration and sustained traumatic brain injury. On postinjury day 3, the patient progressed to adult respiratory distress syndrome (ARDS) refractory to all conventional therapies, prompting the use of extracorporeal membrane oxygenation (ECMO). After 5 days of ECMO support and 3 thrombosed oxygenators, systemic anticoagulation was initiated. After 20 days of ECMO, 15 of which required systemic anticoagulation, the patient was decannulated and transferred to a rehabilitation facility. The patient is currently home without any neurological deficits. Although controversial, ECMO may serve a role as a rescue therapy in ARDS when conventional therapies fail in the brain-injured patient.

Original language	English (US)
Pages (from-to)	597-599
Number of pages	3
Journal	ASAIO Journal
Volume	60
Issue number	5
DOIs	https://doi.org/10.1097/MAT.0000000000000103
State	Published - 2014
Externally published	Yes

Keywords

Adult respiratory distress syndrome
Anticoagulation
Extracorporeal membrane oxygenation
Traumatic brain injury

ASJC Scopus subject areas

Biophysics
Bioengineering
Biomaterials
Biomedical Engineering

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10.1097/MAT.0000000000000103

Cite this

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abstract = "A 21-year-old male trauma patient presented after a motor vehicle crash, witnessed massive aspiration and sustained traumatic brain injury. On postinjury day 3, the patient progressed to adult respiratory distress syndrome (ARDS) refractory to all conventional therapies, prompting the use of extracorporeal membrane oxygenation (ECMO). After 5 days of ECMO support and 3 thrombosed oxygenators, systemic anticoagulation was initiated. After 20 days of ECMO, 15 of which required systemic anticoagulation, the patient was decannulated and transferred to a rehabilitation facility. The patient is currently home without any neurological deficits. Although controversial, ECMO may serve a role as a rescue therapy in ARDS when conventional therapies fail in the brain-injured patient.",

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AU - Messing, Jonathan A.

AU - Agnihothri, Ritesh V.

AU - Van Dusen, Rachel

AU - Najam, Farzad

AU - Dunne, James R.

AU - Honig, Jacqueline R.

AU - Sarani, Babak

PY - 2014

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KW - Anticoagulation

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Prolonged use of extracorporeal membrane oxygenation as a rescue modality following traumatic brain injury

Abstract

Keywords

ASJC Scopus subject areas

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