Progressive intracranial fusiform aneurysms and T-cell immunodeficiency

Juan A. Piantino, Fernando D. Goldenberg, Peter Pytel, Linda Wagner-Weiner, Sameer A. Ansari

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

In the pediatric population, intracranial fusiform aneurysms have been associated with human immunodeficiency virus/acquired immunodeficiency syndrome and rarely with opportunistic infections related to other immunodeficiencies. The HIV virus and other infectious organisms have been implicated in the pathophysiology of these aneurysms. We present a child with T-cell immunodeficiency but no evidence of human immunodeficiency virus or opportunistic intracranial infections that developed progressive bilateral fusiform intracranial aneurysms. Our findings suggest a role of immunodeficiency or inflammation in the formation of some intracranial aneurysms.

Original languageEnglish (US)
Pages (from-to)130-134
Number of pages5
JournalPediatric Neurology
Volume48
Issue number2
DOIs
StatePublished - Feb 1 2013

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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