Prognostic value of left ventricular size measured by echocardiography in infants with total anomalous pulmonary venous drainage

Carlos Oliveira Lima, Lilliam M. Valdes-Cruz, Hugh D. Allen, Suzana Horowitz, David Sahn, Stanley J. Goldberg, Jesus Vargas Barron, Ehud Grenadier

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Left ventricular size may be a determinant of survival in infants with total anomalous pulmonary venous drainage. Right and left ventricular size were measured by M-mode and 2-dimensional (2-D) echocardiography in 13 patients aged 1 day to 4 months (mean weight 4.3 ± 0.42 kg [standard error of the estimate]) who underwent surgery before age 4 months because of severe cyanosis or cardiac failure. Seven patients had venous drainage to a vertical vein, 4 had drainage to the right atrium, and 2 had drainage to the inferior vena cava. Patients were divided into 2 groups: survivors (Group A, n = 8) and nonsurvivors (Group B, n = 5). Death was not statistically related to pulmonary artery pressure, pulmonary venous obstruction, age, or weight at the time of surgery. Right and left ventricular sizes at end-diastole measured from M-mode traces and 2-D echocardiographic 4-chamber views were compared with those from 15 weight-matched control infants. On M-mode and 2-D echocardiography, nonsurvivors had significantly larger right ventricles and smaller left ventricular dimensions than did either control subjects or surviving patients with total anomalous pulmonary venous drainage. The ratio of right to left ventricular size on M-mode and 2-D echocardiography also differed among the 3 infant groups (p <0.001). The ratio of right to left ventricular size differentiated nonsurvivors from survivors and control subjects. Postmortem examinations available in 4 of the 5 nonsurvivors demonstrated that the ratio of right to left ventricular size in the specimens closely agreed with the 2-D echocardiographic ratios. Our study agrees with the impression of other investigators that left ventricular size may be a determinant of survival after repair of total anomalous pulmonary venous drainage.

Original languageEnglish (US)
Pages (from-to)1155-1159
Number of pages5
JournalThe American Journal of Cardiology
Volume51
Issue number7
DOIs
StatePublished - 1983
Externally publishedYes

Fingerprint

Echocardiography
Drainage
Lung
Weights and Measures
Survivors
Cyanosis
Venous Pressure
Diastole
Survival
Inferior Vena Cava
Heart Atria
Pulmonary Artery
Heart Ventricles
Autopsy
Veins
Heart Failure
Research Personnel

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Prognostic value of left ventricular size measured by echocardiography in infants with total anomalous pulmonary venous drainage. / Lima, Carlos Oliveira; Valdes-Cruz, Lilliam M.; Allen, Hugh D.; Horowitz, Suzana; Sahn, David; Goldberg, Stanley J.; Barron, Jesus Vargas; Grenadier, Ehud.

In: The American Journal of Cardiology, Vol. 51, No. 7, 1983, p. 1155-1159.

Research output: Contribution to journalArticle

Lima, CO, Valdes-Cruz, LM, Allen, HD, Horowitz, S, Sahn, D, Goldberg, SJ, Barron, JV & Grenadier, E 1983, 'Prognostic value of left ventricular size measured by echocardiography in infants with total anomalous pulmonary venous drainage', The American Journal of Cardiology, vol. 51, no. 7, pp. 1155-1159. https://doi.org/10.1016/0002-9149(83)90362-4
Lima, Carlos Oliveira ; Valdes-Cruz, Lilliam M. ; Allen, Hugh D. ; Horowitz, Suzana ; Sahn, David ; Goldberg, Stanley J. ; Barron, Jesus Vargas ; Grenadier, Ehud. / Prognostic value of left ventricular size measured by echocardiography in infants with total anomalous pulmonary venous drainage. In: The American Journal of Cardiology. 1983 ; Vol. 51, No. 7. pp. 1155-1159.
@article{e0293cbe290148a59b9a4b5566a9edc8,
title = "Prognostic value of left ventricular size measured by echocardiography in infants with total anomalous pulmonary venous drainage",
abstract = "Left ventricular size may be a determinant of survival in infants with total anomalous pulmonary venous drainage. Right and left ventricular size were measured by M-mode and 2-dimensional (2-D) echocardiography in 13 patients aged 1 day to 4 months (mean weight 4.3 ± 0.42 kg [standard error of the estimate]) who underwent surgery before age 4 months because of severe cyanosis or cardiac failure. Seven patients had venous drainage to a vertical vein, 4 had drainage to the right atrium, and 2 had drainage to the inferior vena cava. Patients were divided into 2 groups: survivors (Group A, n = 8) and nonsurvivors (Group B, n = 5). Death was not statistically related to pulmonary artery pressure, pulmonary venous obstruction, age, or weight at the time of surgery. Right and left ventricular sizes at end-diastole measured from M-mode traces and 2-D echocardiographic 4-chamber views were compared with those from 15 weight-matched control infants. On M-mode and 2-D echocardiography, nonsurvivors had significantly larger right ventricles and smaller left ventricular dimensions than did either control subjects or surviving patients with total anomalous pulmonary venous drainage. The ratio of right to left ventricular size on M-mode and 2-D echocardiography also differed among the 3 infant groups (p <0.001). The ratio of right to left ventricular size differentiated nonsurvivors from survivors and control subjects. Postmortem examinations available in 4 of the 5 nonsurvivors demonstrated that the ratio of right to left ventricular size in the specimens closely agreed with the 2-D echocardiographic ratios. Our study agrees with the impression of other investigators that left ventricular size may be a determinant of survival after repair of total anomalous pulmonary venous drainage.",
author = "Lima, {Carlos Oliveira} and Valdes-Cruz, {Lilliam M.} and Allen, {Hugh D.} and Suzana Horowitz and David Sahn and Goldberg, {Stanley J.} and Barron, {Jesus Vargas} and Ehud Grenadier",
year = "1983",
doi = "10.1016/0002-9149(83)90362-4",
language = "English (US)",
volume = "51",
pages = "1155--1159",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "7",

}

TY - JOUR

T1 - Prognostic value of left ventricular size measured by echocardiography in infants with total anomalous pulmonary venous drainage

AU - Lima, Carlos Oliveira

AU - Valdes-Cruz, Lilliam M.

AU - Allen, Hugh D.

AU - Horowitz, Suzana

AU - Sahn, David

AU - Goldberg, Stanley J.

AU - Barron, Jesus Vargas

AU - Grenadier, Ehud

PY - 1983

Y1 - 1983

N2 - Left ventricular size may be a determinant of survival in infants with total anomalous pulmonary venous drainage. Right and left ventricular size were measured by M-mode and 2-dimensional (2-D) echocardiography in 13 patients aged 1 day to 4 months (mean weight 4.3 ± 0.42 kg [standard error of the estimate]) who underwent surgery before age 4 months because of severe cyanosis or cardiac failure. Seven patients had venous drainage to a vertical vein, 4 had drainage to the right atrium, and 2 had drainage to the inferior vena cava. Patients were divided into 2 groups: survivors (Group A, n = 8) and nonsurvivors (Group B, n = 5). Death was not statistically related to pulmonary artery pressure, pulmonary venous obstruction, age, or weight at the time of surgery. Right and left ventricular sizes at end-diastole measured from M-mode traces and 2-D echocardiographic 4-chamber views were compared with those from 15 weight-matched control infants. On M-mode and 2-D echocardiography, nonsurvivors had significantly larger right ventricles and smaller left ventricular dimensions than did either control subjects or surviving patients with total anomalous pulmonary venous drainage. The ratio of right to left ventricular size on M-mode and 2-D echocardiography also differed among the 3 infant groups (p <0.001). The ratio of right to left ventricular size differentiated nonsurvivors from survivors and control subjects. Postmortem examinations available in 4 of the 5 nonsurvivors demonstrated that the ratio of right to left ventricular size in the specimens closely agreed with the 2-D echocardiographic ratios. Our study agrees with the impression of other investigators that left ventricular size may be a determinant of survival after repair of total anomalous pulmonary venous drainage.

AB - Left ventricular size may be a determinant of survival in infants with total anomalous pulmonary venous drainage. Right and left ventricular size were measured by M-mode and 2-dimensional (2-D) echocardiography in 13 patients aged 1 day to 4 months (mean weight 4.3 ± 0.42 kg [standard error of the estimate]) who underwent surgery before age 4 months because of severe cyanosis or cardiac failure. Seven patients had venous drainage to a vertical vein, 4 had drainage to the right atrium, and 2 had drainage to the inferior vena cava. Patients were divided into 2 groups: survivors (Group A, n = 8) and nonsurvivors (Group B, n = 5). Death was not statistically related to pulmonary artery pressure, pulmonary venous obstruction, age, or weight at the time of surgery. Right and left ventricular sizes at end-diastole measured from M-mode traces and 2-D echocardiographic 4-chamber views were compared with those from 15 weight-matched control infants. On M-mode and 2-D echocardiography, nonsurvivors had significantly larger right ventricles and smaller left ventricular dimensions than did either control subjects or surviving patients with total anomalous pulmonary venous drainage. The ratio of right to left ventricular size on M-mode and 2-D echocardiography also differed among the 3 infant groups (p <0.001). The ratio of right to left ventricular size differentiated nonsurvivors from survivors and control subjects. Postmortem examinations available in 4 of the 5 nonsurvivors demonstrated that the ratio of right to left ventricular size in the specimens closely agreed with the 2-D echocardiographic ratios. Our study agrees with the impression of other investigators that left ventricular size may be a determinant of survival after repair of total anomalous pulmonary venous drainage.

UR - http://www.scopus.com/inward/record.url?scp=0020698102&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020698102&partnerID=8YFLogxK

U2 - 10.1016/0002-9149(83)90362-4

DO - 10.1016/0002-9149(83)90362-4

M3 - Article

VL - 51

SP - 1155

EP - 1159

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 7

ER -