Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway

Patrycja A. Naesgaard, Volker Pönitz, Hildegunn Aarsetoey, Trygve Brügger-Andersen, Heidi Grundt, William Harris, Harry Staines, Dennis W T Nilsen

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: An inverse relationship between cardiovascular risk and levels of vitamin D and omega-3 index may exist. Objectives: To evaluate the prognostic utility of serum 25-hydroxyvitamin D [25(OH)D] in 871 patients with suspected acute coronary syndrome (ACS) and to assess the seasonal correlation between 25(OH)D and the omega-3 index in 456 ACS patients from southwestern Norway. Results: In the univariate analysis the hazard ratio (HR) at 2-year follow-up for all-cause mortality in the highest as compared to the lowest quartile of 25(OH)D in the total population was 0.61 (95% confidence interval (CI), 0.37-1.00), P = 0.050. At 7-year follow-up, the corresponding HR for all-cause mortality was 0.66 (95% CI, 0.49-0.90), P = 0.008, and for females alone 0.51 (95% CI, 0.32-0.83), P = 0.006. Quartile survival did not differ in the multivariable analysis, whereas 25(OH)D <40 nM (

Original languageEnglish (US)
Article number283178
JournalDisease Markers
Volume2015
DOIs
StatePublished - 2015
Externally publishedYes

Fingerprint

Norway
Acute Coronary Syndrome
Vitamin D
Hazards
Confidence Intervals
Mortality
Cholecalciferol
Survival
Serum
Population
25-hydroxyvitamin D

ASJC Scopus subject areas

  • Biochemistry, medical
  • Clinical Biochemistry
  • Molecular Biology
  • Genetics

Cite this

Naesgaard, P. A., Pönitz, V., Aarsetoey, H., Brügger-Andersen, T., Grundt, H., Harris, W., ... Nilsen, D. W. T. (2015). Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway. Disease Markers, 2015, [283178]. https://doi.org/10.1155/2015/283178

Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway. / Naesgaard, Patrycja A.; Pönitz, Volker; Aarsetoey, Hildegunn; Brügger-Andersen, Trygve; Grundt, Heidi; Harris, William; Staines, Harry; Nilsen, Dennis W T.

In: Disease Markers, Vol. 2015, 283178, 2015.

Research output: Contribution to journalArticle

Naesgaard, PA, Pönitz, V, Aarsetoey, H, Brügger-Andersen, T, Grundt, H, Harris, W, Staines, H & Nilsen, DWT 2015, 'Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway', Disease Markers, vol. 2015, 283178. https://doi.org/10.1155/2015/283178
Naesgaard PA, Pönitz V, Aarsetoey H, Brügger-Andersen T, Grundt H, Harris W et al. Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway. Disease Markers. 2015;2015. 283178. https://doi.org/10.1155/2015/283178
Naesgaard, Patrycja A. ; Pönitz, Volker ; Aarsetoey, Hildegunn ; Brügger-Andersen, Trygve ; Grundt, Heidi ; Harris, William ; Staines, Harry ; Nilsen, Dennis W T. / Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway. In: Disease Markers. 2015 ; Vol. 2015.
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AU - Harris, William

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