Prognostic importance of superior diaphragmatic adenopathy at computed tomography in patients with resectable hepatic metastases from colorectal carcinoma

Rizwan Aslam, Fergus Coakley, Gethin Williams, Benjamin M. Yeh, Bonnie N. Joe, Marlene B. Zuraek, Robert S. Warren

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

PURPOSE: To determine the prognostic importance of superior diaphragmatic adenopathy at CT in patients with resectable hepatic metastases from colorectal carcinoma. MATERIALS AND METHODS: We retrospectively identified 85 patients who underwent contrast-enhanced abdominal computed tomography (CT) at our institution before surgical resection of hepatic metastases from colorectal carcinoma. The study group consisted of 45 men and 40 women with a mean age of 60 years (range, 27-89 years). The presence, size, and number of superior diaphragmatic nodes were recorded on preoperative CT images. Kaplan-Meier analysis was used to investigate the association between the presence, number, and size of superior diaphragmatic nodes and postoperative outcome. RESULTS: One or more superior diaphragmatic nodes were seen on preoperative CT in 43 (51%) of 85 patients, and 29 (34%) patients had nodes of 5 mm or more in short-axis diameter. After a median follow-up of 599 days (range, 3-1960 days), 49 patients were alive, and 36 were dead. Kaplan-Meier analysis showed no association between the presence (P = 0.67), size (P = 0.74), or number (P = 0.95) of superior diaphragmatic nodes and patient outcome. CONCLUSIONS: The presence, size, or number of superior diaphragmatic nodes at preoperative CT are unrelated to postoperative outcome in patients with resectable hepatic metastases from colorectal carcinoma, suggesting that superior diaphragmatic adenopathy in this setting may be reactive rather than metastatic.

Original languageEnglish (US)
Pages (from-to)173-177
Number of pages5
JournalJournal of Computer Assisted Tomography
Volume32
Issue number2
DOIs
StatePublished - Mar 2008
Externally publishedYes

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Colorectal Neoplasms
Tomography
Neoplasm Metastasis
Liver
Kaplan-Meier Estimate
Lymphadenopathy

Keywords

  • Colorectal cancer
  • CT
  • Superior diaphragmatic adenopathy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Prognostic importance of superior diaphragmatic adenopathy at computed tomography in patients with resectable hepatic metastases from colorectal carcinoma. / Aslam, Rizwan; Coakley, Fergus; Williams, Gethin; Yeh, Benjamin M.; Joe, Bonnie N.; Zuraek, Marlene B.; Warren, Robert S.

In: Journal of Computer Assisted Tomography, Vol. 32, No. 2, 03.2008, p. 173-177.

Research output: Contribution to journalArticle

Aslam, Rizwan ; Coakley, Fergus ; Williams, Gethin ; Yeh, Benjamin M. ; Joe, Bonnie N. ; Zuraek, Marlene B. ; Warren, Robert S. / Prognostic importance of superior diaphragmatic adenopathy at computed tomography in patients with resectable hepatic metastases from colorectal carcinoma. In: Journal of Computer Assisted Tomography. 2008 ; Vol. 32, No. 2. pp. 173-177.
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abstract = "PURPOSE: To determine the prognostic importance of superior diaphragmatic adenopathy at CT in patients with resectable hepatic metastases from colorectal carcinoma. MATERIALS AND METHODS: We retrospectively identified 85 patients who underwent contrast-enhanced abdominal computed tomography (CT) at our institution before surgical resection of hepatic metastases from colorectal carcinoma. The study group consisted of 45 men and 40 women with a mean age of 60 years (range, 27-89 years). The presence, size, and number of superior diaphragmatic nodes were recorded on preoperative CT images. Kaplan-Meier analysis was used to investigate the association between the presence, number, and size of superior diaphragmatic nodes and postoperative outcome. RESULTS: One or more superior diaphragmatic nodes were seen on preoperative CT in 43 (51{\%}) of 85 patients, and 29 (34{\%}) patients had nodes of 5 mm or more in short-axis diameter. After a median follow-up of 599 days (range, 3-1960 days), 49 patients were alive, and 36 were dead. Kaplan-Meier analysis showed no association between the presence (P = 0.67), size (P = 0.74), or number (P = 0.95) of superior diaphragmatic nodes and patient outcome. CONCLUSIONS: The presence, size, or number of superior diaphragmatic nodes at preoperative CT are unrelated to postoperative outcome in patients with resectable hepatic metastases from colorectal carcinoma, suggesting that superior diaphragmatic adenopathy in this setting may be reactive rather than metastatic.",
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N2 - PURPOSE: To determine the prognostic importance of superior diaphragmatic adenopathy at CT in patients with resectable hepatic metastases from colorectal carcinoma. MATERIALS AND METHODS: We retrospectively identified 85 patients who underwent contrast-enhanced abdominal computed tomography (CT) at our institution before surgical resection of hepatic metastases from colorectal carcinoma. The study group consisted of 45 men and 40 women with a mean age of 60 years (range, 27-89 years). The presence, size, and number of superior diaphragmatic nodes were recorded on preoperative CT images. Kaplan-Meier analysis was used to investigate the association between the presence, number, and size of superior diaphragmatic nodes and postoperative outcome. RESULTS: One or more superior diaphragmatic nodes were seen on preoperative CT in 43 (51%) of 85 patients, and 29 (34%) patients had nodes of 5 mm or more in short-axis diameter. After a median follow-up of 599 days (range, 3-1960 days), 49 patients were alive, and 36 were dead. Kaplan-Meier analysis showed no association between the presence (P = 0.67), size (P = 0.74), or number (P = 0.95) of superior diaphragmatic nodes and patient outcome. CONCLUSIONS: The presence, size, or number of superior diaphragmatic nodes at preoperative CT are unrelated to postoperative outcome in patients with resectable hepatic metastases from colorectal carcinoma, suggesting that superior diaphragmatic adenopathy in this setting may be reactive rather than metastatic.

AB - PURPOSE: To determine the prognostic importance of superior diaphragmatic adenopathy at CT in patients with resectable hepatic metastases from colorectal carcinoma. MATERIALS AND METHODS: We retrospectively identified 85 patients who underwent contrast-enhanced abdominal computed tomography (CT) at our institution before surgical resection of hepatic metastases from colorectal carcinoma. The study group consisted of 45 men and 40 women with a mean age of 60 years (range, 27-89 years). The presence, size, and number of superior diaphragmatic nodes were recorded on preoperative CT images. Kaplan-Meier analysis was used to investigate the association between the presence, number, and size of superior diaphragmatic nodes and postoperative outcome. RESULTS: One or more superior diaphragmatic nodes were seen on preoperative CT in 43 (51%) of 85 patients, and 29 (34%) patients had nodes of 5 mm or more in short-axis diameter. After a median follow-up of 599 days (range, 3-1960 days), 49 patients were alive, and 36 were dead. Kaplan-Meier analysis showed no association between the presence (P = 0.67), size (P = 0.74), or number (P = 0.95) of superior diaphragmatic nodes and patient outcome. CONCLUSIONS: The presence, size, or number of superior diaphragmatic nodes at preoperative CT are unrelated to postoperative outcome in patients with resectable hepatic metastases from colorectal carcinoma, suggesting that superior diaphragmatic adenopathy in this setting may be reactive rather than metastatic.

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