Prognostic impact of chromosome aberrations in ovarian cancer

Tanja Pejovic, A. Himmelmann, S. Heim, N. Mandahl, U. M. Floderus, S. Furgyik, B. Elmfors, G. Helm, H. Willen, F. Mitelmanl

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Clinico-cytogenetic correlations were assessed in 88 patients with malignant ovarian tumours. Cytogenetic analysis of the primary tumours yielded normal karyotype (N) in 33 patients and abnormal karyotypes (A) in 55 patients. Within the A group, seven tumours had simple abnormalities (AS), i.e., numerical changes only or a single structural aberration, and 48 had karyotypes with complex aberrations (AC). A correlation analysis between groups N and A revealed that cytogenetic abnormalities were more often found among seropapillary tumours, and that cases with abnormal karyotypes on average were of higher stage and more often had residual tumour mass after initial surgery (P

Original languageEnglish (US)
Pages (from-to)282-286
Number of pages5
JournalBritish Journal of Cancer
Volume65
Issue number2
StatePublished - 1992
Externally publishedYes

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Chromosome Aberrations
Ovarian Neoplasms
Abnormal Karyotype
Karyotype
Neoplasms
Cytogenetic Analysis
Residual Neoplasm
Cytogenetics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Pejovic, T., Himmelmann, A., Heim, S., Mandahl, N., Floderus, U. M., Furgyik, S., ... Mitelmanl, F. (1992). Prognostic impact of chromosome aberrations in ovarian cancer. British Journal of Cancer, 65(2), 282-286.

Prognostic impact of chromosome aberrations in ovarian cancer. / Pejovic, Tanja; Himmelmann, A.; Heim, S.; Mandahl, N.; Floderus, U. M.; Furgyik, S.; Elmfors, B.; Helm, G.; Willen, H.; Mitelmanl, F.

In: British Journal of Cancer, Vol. 65, No. 2, 1992, p. 282-286.

Research output: Contribution to journalArticle

Pejovic, T, Himmelmann, A, Heim, S, Mandahl, N, Floderus, UM, Furgyik, S, Elmfors, B, Helm, G, Willen, H & Mitelmanl, F 1992, 'Prognostic impact of chromosome aberrations in ovarian cancer', British Journal of Cancer, vol. 65, no. 2, pp. 282-286.
Pejovic T, Himmelmann A, Heim S, Mandahl N, Floderus UM, Furgyik S et al. Prognostic impact of chromosome aberrations in ovarian cancer. British Journal of Cancer. 1992;65(2):282-286.
Pejovic, Tanja ; Himmelmann, A. ; Heim, S. ; Mandahl, N. ; Floderus, U. M. ; Furgyik, S. ; Elmfors, B. ; Helm, G. ; Willen, H. ; Mitelmanl, F. / Prognostic impact of chromosome aberrations in ovarian cancer. In: British Journal of Cancer. 1992 ; Vol. 65, No. 2. pp. 282-286.
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