Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation: Insights from theNational Cardiovascular Data Registry

Jonathan C. Hsu, Paul D. Varosy, Craig S. Parzynski, Sarwat I. Chaudhry, Thomas Dewland, Jeptha P. Curtis, Gregory M. Marcus

Research output: Contribution to journalArticle

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Abstract

Background Implantable cardioverter-defibrillator (ICD) procedures performed later in the day and on weekends/ holidays may be associated with adverse events due to a variety of factors including operator fatigue, handoffs, reduced staffing, and limited resource availability. We sought to determine whether patients implanted with ICDs in the afternoon/ evening and on weekends/holidays are at increased risk for adverse events. Methods We studied 148,004 first-time ICD recipients in the National Cardiovascular Data Registry-ICD Registry implanted between April 2010 and March 2012. Using hierarchical multivariable logistic regression adjusting for patient, implanting physician, and hospital characteristics, we examined the association between both ICD implant start time and day of week with any complication, a prolonged hospital stay, and mortality. Results Most ICDimplants (52.6%; n = 77,853) were performed in the morning (6 AM-12 PM) and during the regular workweek (97.5%; n = 144,266). After multivariable adjustment, ICD recipients implanted in the afternoon (12 PM-5 PM)/evening (5 PM-6 AM) compared with the morning experienced a greater odds of any complication (odds ratio [OR] 1.08; 95%CI 1.01-1.15; P = .0168), hospital stay N1 day (OR 1.29; 95% CI 1.25-1.33; P b .0001) but not inhospital death (OR 1.06; 95% CI 0.88-1.27; P = .5322). Implantable cardioverter-defibrillator recipients implanted on weekend/holidays compared with the mid-workweek also experienced a significantly greater odds of hospital stay N1 day (OR 1.40; 95% CI 1.29-1.53; P b .0001), no statistically significant differences in total complications (OR 1.14; 95% CI 0.96-1.36; P = .1371), and a trend toward more inhospital death (OR 1.52; 95% CI 0.98-2.38; P = .0642). Conclusions In a large, real-world population, ICD recipients implanted in the afternoon/evening and on weekends/ holidays more often experienced adverse events, particularly prolonged hospital stays.

Original languageEnglish (US)
Pages (from-to)45-52.e3
JournalAmerican Heart Journal
Volume169
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

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Implantable Defibrillators
Registries
Holidays
Odds Ratio
Length of Stay
Hospital Mortality
Fatigue
Logistic Models
Physicians
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

Cite this

Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation : Insights from theNational Cardiovascular Data Registry. / Hsu, Jonathan C.; Varosy, Paul D.; Parzynski, Craig S.; Chaudhry, Sarwat I.; Dewland, Thomas; Curtis, Jeptha P.; Marcus, Gregory M.

In: American Heart Journal, Vol. 169, No. 1, 2014, p. 45-52.e3.

Research output: Contribution to journalArticle

Hsu, Jonathan C. ; Varosy, Paul D. ; Parzynski, Craig S. ; Chaudhry, Sarwat I. ; Dewland, Thomas ; Curtis, Jeptha P. ; Marcus, Gregory M. / Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation : Insights from theNational Cardiovascular Data Registry. In: American Heart Journal. 2014 ; Vol. 169, No. 1. pp. 45-52.e3.
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abstract = "Background Implantable cardioverter-defibrillator (ICD) procedures performed later in the day and on weekends/ holidays may be associated with adverse events due to a variety of factors including operator fatigue, handoffs, reduced staffing, and limited resource availability. We sought to determine whether patients implanted with ICDs in the afternoon/ evening and on weekends/holidays are at increased risk for adverse events. Methods We studied 148,004 first-time ICD recipients in the National Cardiovascular Data Registry-ICD Registry implanted between April 2010 and March 2012. Using hierarchical multivariable logistic regression adjusting for patient, implanting physician, and hospital characteristics, we examined the association between both ICD implant start time and day of week with any complication, a prolonged hospital stay, and mortality. Results Most ICDimplants (52.6{\%}; n = 77,853) were performed in the morning (6 AM-12 PM) and during the regular workweek (97.5{\%}; n = 144,266). After multivariable adjustment, ICD recipients implanted in the afternoon (12 PM-5 PM)/evening (5 PM-6 AM) compared with the morning experienced a greater odds of any complication (odds ratio [OR] 1.08; 95{\%}CI 1.01-1.15; P = .0168), hospital stay N1 day (OR 1.29; 95{\%} CI 1.25-1.33; P b .0001) but not inhospital death (OR 1.06; 95{\%} CI 0.88-1.27; P = .5322). Implantable cardioverter-defibrillator recipients implanted on weekend/holidays compared with the mid-workweek also experienced a significantly greater odds of hospital stay N1 day (OR 1.40; 95{\%} CI 1.29-1.53; P b .0001), no statistically significant differences in total complications (OR 1.14; 95{\%} CI 0.96-1.36; P = .1371), and a trend toward more inhospital death (OR 1.52; 95{\%} CI 0.98-2.38; P = .0642). Conclusions In a large, real-world population, ICD recipients implanted in the afternoon/evening and on weekends/ holidays more often experienced adverse events, particularly prolonged hospital stays.",
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T1 - Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation

T2 - Insights from theNational Cardiovascular Data Registry

AU - Hsu, Jonathan C.

AU - Varosy, Paul D.

AU - Parzynski, Craig S.

AU - Chaudhry, Sarwat I.

AU - Dewland, Thomas

AU - Curtis, Jeptha P.

AU - Marcus, Gregory M.

PY - 2014

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N2 - Background Implantable cardioverter-defibrillator (ICD) procedures performed later in the day and on weekends/ holidays may be associated with adverse events due to a variety of factors including operator fatigue, handoffs, reduced staffing, and limited resource availability. We sought to determine whether patients implanted with ICDs in the afternoon/ evening and on weekends/holidays are at increased risk for adverse events. Methods We studied 148,004 first-time ICD recipients in the National Cardiovascular Data Registry-ICD Registry implanted between April 2010 and March 2012. Using hierarchical multivariable logistic regression adjusting for patient, implanting physician, and hospital characteristics, we examined the association between both ICD implant start time and day of week with any complication, a prolonged hospital stay, and mortality. Results Most ICDimplants (52.6%; n = 77,853) were performed in the morning (6 AM-12 PM) and during the regular workweek (97.5%; n = 144,266). After multivariable adjustment, ICD recipients implanted in the afternoon (12 PM-5 PM)/evening (5 PM-6 AM) compared with the morning experienced a greater odds of any complication (odds ratio [OR] 1.08; 95%CI 1.01-1.15; P = .0168), hospital stay N1 day (OR 1.29; 95% CI 1.25-1.33; P b .0001) but not inhospital death (OR 1.06; 95% CI 0.88-1.27; P = .5322). Implantable cardioverter-defibrillator recipients implanted on weekend/holidays compared with the mid-workweek also experienced a significantly greater odds of hospital stay N1 day (OR 1.40; 95% CI 1.29-1.53; P b .0001), no statistically significant differences in total complications (OR 1.14; 95% CI 0.96-1.36; P = .1371), and a trend toward more inhospital death (OR 1.52; 95% CI 0.98-2.38; P = .0642). Conclusions In a large, real-world population, ICD recipients implanted in the afternoon/evening and on weekends/ holidays more often experienced adverse events, particularly prolonged hospital stays.

AB - Background Implantable cardioverter-defibrillator (ICD) procedures performed later in the day and on weekends/ holidays may be associated with adverse events due to a variety of factors including operator fatigue, handoffs, reduced staffing, and limited resource availability. We sought to determine whether patients implanted with ICDs in the afternoon/ evening and on weekends/holidays are at increased risk for adverse events. Methods We studied 148,004 first-time ICD recipients in the National Cardiovascular Data Registry-ICD Registry implanted between April 2010 and March 2012. Using hierarchical multivariable logistic regression adjusting for patient, implanting physician, and hospital characteristics, we examined the association between both ICD implant start time and day of week with any complication, a prolonged hospital stay, and mortality. Results Most ICDimplants (52.6%; n = 77,853) were performed in the morning (6 AM-12 PM) and during the regular workweek (97.5%; n = 144,266). After multivariable adjustment, ICD recipients implanted in the afternoon (12 PM-5 PM)/evening (5 PM-6 AM) compared with the morning experienced a greater odds of any complication (odds ratio [OR] 1.08; 95%CI 1.01-1.15; P = .0168), hospital stay N1 day (OR 1.29; 95% CI 1.25-1.33; P b .0001) but not inhospital death (OR 1.06; 95% CI 0.88-1.27; P = .5322). Implantable cardioverter-defibrillator recipients implanted on weekend/holidays compared with the mid-workweek also experienced a significantly greater odds of hospital stay N1 day (OR 1.40; 95% CI 1.29-1.53; P b .0001), no statistically significant differences in total complications (OR 1.14; 95% CI 0.96-1.36; P = .1371), and a trend toward more inhospital death (OR 1.52; 95% CI 0.98-2.38; P = .0642). Conclusions In a large, real-world population, ICD recipients implanted in the afternoon/evening and on weekends/ holidays more often experienced adverse events, particularly prolonged hospital stays.

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