Primate follicular development and oocyte maturation in vitro

Jing Xu, Min Xu, Marcelo P. Bernuci, Thomas E. Fisher, Lonnie D. Shea, Teresa K. Woodruff, Mary Zelinski, Richard Stouffer

    Research output: Chapter in Book/Report/Conference proceedingChapter

    31 Citations (Scopus)

    Abstract

    The factors and processes involved in primate follicular development are complex and not fully understood. An encapsulated three-dimensional (3D) follicle culture system could be a valuable in vitro model to study the dynamics and regulation of folliculogenesis in intact individual follicles in primates. Besides the research relevance, in vitro follicle maturation (IFM) is emerging as a promising approach to offer options for fertility preservation in female patients with cancer. This review summarizes the current published data on in vitro follicular development from the preantral to small antral stage in nonhuman primates, including follicle survival and growth, endocrine (ovarian steroid hormone) and paracrine/autocrine (local factor) function, as well as oocyte maturation and fertilization. Future directions include major challenges and strategies to further improve follicular growth and differentiation with oocytes competent for in vitro fertilization and subsequent embryonic development, as well as opportunities to investigate primate folliculogenesis by utilizing this 3D culture system. The information may be valuable in identifying optimal conditions for human follicle culture, with the ultimate goal of translating the experimental results and products to patients, thereby facilitating diagnostic and therapeutic approaches for female fertility.

    Original languageEnglish (US)
    Title of host publicationAdvances in Experimental Medicine and Biology
    Pages43-67
    Number of pages25
    Volume761
    DOIs
    StatePublished - 2013

    Publication series

    NameAdvances in Experimental Medicine and Biology
    Volume761
    ISSN (Print)00652598

    Fingerprint

    In Vitro Oocyte Maturation Techniques
    Primates
    Oocytes
    Steroid hormones
    Fertility Preservation
    Fertilization in Vitro
    Growth
    Fertilization
    Embryonic Development
    Fertility
    Steroids
    Hormones
    Survival
    Research
    In Vitro Techniques
    Neoplasms

    Keywords

    • Fertility preservation
    • Folliculogenesis
    • In vitro follicle maturation
    • Primate
    • Three-dimensional follicle culture

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)
    • Medicine(all)

    Cite this

    Xu, J., Xu, M., Bernuci, M. P., Fisher, T. E., Shea, L. D., Woodruff, T. K., ... Stouffer, R. (2013). Primate follicular development and oocyte maturation in vitro. In Advances in Experimental Medicine and Biology (Vol. 761, pp. 43-67). (Advances in Experimental Medicine and Biology; Vol. 761). https://doi.org/10.1007/978-1-4614-8214-7-5

    Primate follicular development and oocyte maturation in vitro. / Xu, Jing; Xu, Min; Bernuci, Marcelo P.; Fisher, Thomas E.; Shea, Lonnie D.; Woodruff, Teresa K.; Zelinski, Mary; Stouffer, Richard.

    Advances in Experimental Medicine and Biology. Vol. 761 2013. p. 43-67 (Advances in Experimental Medicine and Biology; Vol. 761).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Xu, J, Xu, M, Bernuci, MP, Fisher, TE, Shea, LD, Woodruff, TK, Zelinski, M & Stouffer, R 2013, Primate follicular development and oocyte maturation in vitro. in Advances in Experimental Medicine and Biology. vol. 761, Advances in Experimental Medicine and Biology, vol. 761, pp. 43-67. https://doi.org/10.1007/978-1-4614-8214-7-5
    Xu J, Xu M, Bernuci MP, Fisher TE, Shea LD, Woodruff TK et al. Primate follicular development and oocyte maturation in vitro. In Advances in Experimental Medicine and Biology. Vol. 761. 2013. p. 43-67. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-1-4614-8214-7-5
    Xu, Jing ; Xu, Min ; Bernuci, Marcelo P. ; Fisher, Thomas E. ; Shea, Lonnie D. ; Woodruff, Teresa K. ; Zelinski, Mary ; Stouffer, Richard. / Primate follicular development and oocyte maturation in vitro. Advances in Experimental Medicine and Biology. Vol. 761 2013. pp. 43-67 (Advances in Experimental Medicine and Biology).
    @inbook{4fa6c7c854b64e29b2645afcfde3a96d,
    title = "Primate follicular development and oocyte maturation in vitro",
    abstract = "The factors and processes involved in primate follicular development are complex and not fully understood. An encapsulated three-dimensional (3D) follicle culture system could be a valuable in vitro model to study the dynamics and regulation of folliculogenesis in intact individual follicles in primates. Besides the research relevance, in vitro follicle maturation (IFM) is emerging as a promising approach to offer options for fertility preservation in female patients with cancer. This review summarizes the current published data on in vitro follicular development from the preantral to small antral stage in nonhuman primates, including follicle survival and growth, endocrine (ovarian steroid hormone) and paracrine/autocrine (local factor) function, as well as oocyte maturation and fertilization. Future directions include major challenges and strategies to further improve follicular growth and differentiation with oocytes competent for in vitro fertilization and subsequent embryonic development, as well as opportunities to investigate primate folliculogenesis by utilizing this 3D culture system. The information may be valuable in identifying optimal conditions for human follicle culture, with the ultimate goal of translating the experimental results and products to patients, thereby facilitating diagnostic and therapeutic approaches for female fertility.",
    keywords = "Fertility preservation, Folliculogenesis, In vitro follicle maturation, Primate, Three-dimensional follicle culture",
    author = "Jing Xu and Min Xu and Bernuci, {Marcelo P.} and Fisher, {Thomas E.} and Shea, {Lonnie D.} and Woodruff, {Teresa K.} and Mary Zelinski and Richard Stouffer",
    year = "2013",
    doi = "10.1007/978-1-4614-8214-7-5",
    language = "English (US)",
    isbn = "9781461482130",
    volume = "761",
    series = "Advances in Experimental Medicine and Biology",
    pages = "43--67",
    booktitle = "Advances in Experimental Medicine and Biology",

    }

    TY - CHAP

    T1 - Primate follicular development and oocyte maturation in vitro

    AU - Xu, Jing

    AU - Xu, Min

    AU - Bernuci, Marcelo P.

    AU - Fisher, Thomas E.

    AU - Shea, Lonnie D.

    AU - Woodruff, Teresa K.

    AU - Zelinski, Mary

    AU - Stouffer, Richard

    PY - 2013

    Y1 - 2013

    N2 - The factors and processes involved in primate follicular development are complex and not fully understood. An encapsulated three-dimensional (3D) follicle culture system could be a valuable in vitro model to study the dynamics and regulation of folliculogenesis in intact individual follicles in primates. Besides the research relevance, in vitro follicle maturation (IFM) is emerging as a promising approach to offer options for fertility preservation in female patients with cancer. This review summarizes the current published data on in vitro follicular development from the preantral to small antral stage in nonhuman primates, including follicle survival and growth, endocrine (ovarian steroid hormone) and paracrine/autocrine (local factor) function, as well as oocyte maturation and fertilization. Future directions include major challenges and strategies to further improve follicular growth and differentiation with oocytes competent for in vitro fertilization and subsequent embryonic development, as well as opportunities to investigate primate folliculogenesis by utilizing this 3D culture system. The information may be valuable in identifying optimal conditions for human follicle culture, with the ultimate goal of translating the experimental results and products to patients, thereby facilitating diagnostic and therapeutic approaches for female fertility.

    AB - The factors and processes involved in primate follicular development are complex and not fully understood. An encapsulated three-dimensional (3D) follicle culture system could be a valuable in vitro model to study the dynamics and regulation of folliculogenesis in intact individual follicles in primates. Besides the research relevance, in vitro follicle maturation (IFM) is emerging as a promising approach to offer options for fertility preservation in female patients with cancer. This review summarizes the current published data on in vitro follicular development from the preantral to small antral stage in nonhuman primates, including follicle survival and growth, endocrine (ovarian steroid hormone) and paracrine/autocrine (local factor) function, as well as oocyte maturation and fertilization. Future directions include major challenges and strategies to further improve follicular growth and differentiation with oocytes competent for in vitro fertilization and subsequent embryonic development, as well as opportunities to investigate primate folliculogenesis by utilizing this 3D culture system. The information may be valuable in identifying optimal conditions for human follicle culture, with the ultimate goal of translating the experimental results and products to patients, thereby facilitating diagnostic and therapeutic approaches for female fertility.

    KW - Fertility preservation

    KW - Folliculogenesis

    KW - In vitro follicle maturation

    KW - Primate

    KW - Three-dimensional follicle culture

    UR - http://www.scopus.com/inward/record.url?scp=84893041885&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84893041885&partnerID=8YFLogxK

    U2 - 10.1007/978-1-4614-8214-7-5

    DO - 10.1007/978-1-4614-8214-7-5

    M3 - Chapter

    SN - 9781461482130

    VL - 761

    T3 - Advances in Experimental Medicine and Biology

    SP - 43

    EP - 67

    BT - Advances in Experimental Medicine and Biology

    ER -