Primary Extranodal Nodular Lymphocyte Predominant Hodgkin Lymphoma Involving the Thyroid

Research output: Contribution to journalArticle

Abstract

Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an uncommon lymphoma that accounts for 3–8% of all Hodgkin lymphomas. NLPHL typically presents as early stage disease with localized peripheral lymphadenopathy. Involvement of extranodal sites at the time of presentation occurs in 6% of cases and most commonly involves the spleen, liver, bone marrow, and Waldeyer ring. Primary extranodal NLPHL is exceedingly rare. We describe the first reported case involving the thyroid and review the six other previously described cases of primary extranodal NLPHL.

Original languageEnglish (US)
JournalHead and Neck Pathology
DOIs
StatePublished - Jan 1 2019

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Hodgkin Disease
Thyroid Gland
Lymphoma
Spleen
Bone Marrow
Liver

Keywords

  • Extranodal
  • Hodgkin
  • Lymphoma
  • Nodular lymphocyte-predominant Hodgkin’s lymphoma
  • Thyroid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Otorhinolaryngology
  • Oncology

Cite this

@article{391292391b3a40b7ac0f07cb0327d593,
title = "Primary Extranodal Nodular Lymphocyte Predominant Hodgkin Lymphoma Involving the Thyroid",
abstract = "Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an uncommon lymphoma that accounts for 3–8{\%} of all Hodgkin lymphomas. NLPHL typically presents as early stage disease with localized peripheral lymphadenopathy. Involvement of extranodal sites at the time of presentation occurs in 6{\%} of cases and most commonly involves the spleen, liver, bone marrow, and Waldeyer ring. Primary extranodal NLPHL is exceedingly rare. We describe the first reported case involving the thyroid and review the six other previously described cases of primary extranodal NLPHL.",
keywords = "Extranodal, Hodgkin, Lymphoma, Nodular lymphocyte-predominant Hodgkin’s lymphoma, Thyroid",
author = "Williams, {Todd P.} and Phil Raess and Rita Braziel and Michael Cascio",
year = "2019",
month = "1",
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doi = "10.1007/s12105-019-01052-y",
language = "English (US)",
journal = "Head and Neck Pathology",
issn = "1936-055X",
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TY - JOUR

T1 - Primary Extranodal Nodular Lymphocyte Predominant Hodgkin Lymphoma Involving the Thyroid

AU - Williams, Todd P.

AU - Raess, Phil

AU - Braziel, Rita

AU - Cascio, Michael

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an uncommon lymphoma that accounts for 3–8% of all Hodgkin lymphomas. NLPHL typically presents as early stage disease with localized peripheral lymphadenopathy. Involvement of extranodal sites at the time of presentation occurs in 6% of cases and most commonly involves the spleen, liver, bone marrow, and Waldeyer ring. Primary extranodal NLPHL is exceedingly rare. We describe the first reported case involving the thyroid and review the six other previously described cases of primary extranodal NLPHL.

AB - Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an uncommon lymphoma that accounts for 3–8% of all Hodgkin lymphomas. NLPHL typically presents as early stage disease with localized peripheral lymphadenopathy. Involvement of extranodal sites at the time of presentation occurs in 6% of cases and most commonly involves the spleen, liver, bone marrow, and Waldeyer ring. Primary extranodal NLPHL is exceedingly rare. We describe the first reported case involving the thyroid and review the six other previously described cases of primary extranodal NLPHL.

KW - Extranodal

KW - Hodgkin

KW - Lymphoma

KW - Nodular lymphocyte-predominant Hodgkin’s lymphoma

KW - Thyroid

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