Prevalence of premature urinary luteinizing hormone surges in women with regular menstrual cycles and its effect on implantation of frozen-thawed embryos

Stephan Krotz, Laurie J. McKenzie, Pauline Cisneros, John Buster, Paula Amato, Sandra Carson

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objective: To determine the frequency and effect of premature luteinizing hormone (LH) surges on pregnancy rates in women with regular menstrual cycles. Design: Retrospective cohort study. Setting: Assisted Reproductive Technology Program at private medical college. Patient(s): Regularly menstruating women undergoing frozen embryo transfer (ET). Intervention(s): Detection of urinary LH surges with an RIA kit during natural-cycle frozen-embryos transfer. Main Outcome Measure(s): Incidence of premature LH surges and pregnancy outcomes. Result(s): Eighty-eight (46.8%) of 188 regularly menstruating women had premature LH surges and 33 (37%) of those 88 had multiple premature LH surges. Pregnancy rates per ET are similar between women with and without premature LH surges. Conclusion(s): A high percentage of normally cycling women demonstrate premature urinary LH surges without an effect on outcome of frozen-thawed ETs.

Original languageEnglish (US)
Pages (from-to)1742-1744
Number of pages3
JournalFertility and sterility
Volume83
Issue number6
DOIs
StatePublished - Jun 2005
Externally publishedYes

Keywords

  • Luteinizing hormone
  • Natural-cycle frozen-embryo transfer
  • Premature surge
  • Urinary LH kit

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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