Prevalence of hematopoietic cell transplant survivors in the United States

Navneet S. Majhail, Li Tao, Christopher Bredeson, Stella Davies, Jason Dehn, James L. Gajewski, Theresa Hahn, Ann Jakubowski, Steven Joffe, Hillard M. Lazarus, Susan K. Parsons, Kim Robien, Stephanie J. Lee, Karen M. Kuntz

    Research output: Contribution to journalArticle

    102 Scopus citations

    Abstract

    Advances in hematopoietic cell transplantation (HCT) have led to an increasing number of transplant survivors. To adequately support their healthcare needs, there is a need to know the prevalence of HCT survivors. We used data on 170,628 recipients of autologous and allogeneic HCT reported to the Center for International Blood and Marrow Transplant Research from 1968 to 2009 to estimate the current and future number of HCT survivors in the United States. Stacked cohort simulation models were used to estimate the number of HCT survivors in the United States in 2009 and to make projections for HCT survivors by the year 2030. There were 108,900 (range, 100,500 to 115,200) HCT survivors in the United States in 2009. This included 67,000 autologous HCT and 41,900 allogeneic HCT survivors. The number of HCT survivors is estimated to increase by 2.5 times by the year 2020 (242,000 survivors) and 5 times by the year 2030 (502,000 survivors). By 2030, the age at transplant will be<18years for 14% of all survivors (n=64,000), 18 to 59years for 61% survivors (n=276,000), and 60years and older for 25% of survivors (n=113,000). In coming decades, a large number of individuals will be HCT survivors. Transplant center providers, hematologists, oncologists, primary care physicians, and other specialty providers will need to be familiar with the unique and complex health issues faced by this population.

    Original languageEnglish (US)
    Pages (from-to)1498-1501
    Number of pages4
    JournalBiology of Blood and Marrow Transplantation
    Volume19
    Issue number10
    DOIs
    StatePublished - Oct 1 2013

    Keywords

    • Allogeneic
    • Autologous
    • Hematopoietic cell transplantation
    • Prevalence
    • Survivors

    ASJC Scopus subject areas

    • Hematology
    • Transplantation

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  • Cite this

    Majhail, N. S., Tao, L., Bredeson, C., Davies, S., Dehn, J., Gajewski, J. L., Hahn, T., Jakubowski, A., Joffe, S., Lazarus, H. M., Parsons, S. K., Robien, K., Lee, S. J., & Kuntz, K. M. (2013). Prevalence of hematopoietic cell transplant survivors in the United States. Biology of Blood and Marrow Transplantation, 19(10), 1498-1501. https://doi.org/10.1016/j.bbmt.2013.07.020