TY - JOUR
T1 - Prevalence and burden of chronic bronchitis symptoms
T2 - Results from the BOLD study
AU - the BOLD collaborators
AU - Mejza, Filip
AU - Gnatiuc, Louisa
AU - Buist, A. Sonia
AU - Vollmer, William M.
AU - Lamprecht, Bernd
AU - Obaseki, Daniel O.
AU - Nastalek, Pawel
AU - Nizankowska-Mogilnicka, Ewa
AU - Burney, Peter G.J.
AU - Zhong, Nan Shan
AU - Liu, Shengming
AU - Lu, Jiachun
AU - Ran, Pixin
AU - Wang, Dali
AU - Zheng, Jingping
AU - Zhou, Yumin
AU - Kocabaş, Ali
AU - Hancioglu, Attila
AU - Hanta, Ismail
AU - Kuleci, Sedat
AU - Turkyilmaz, Ahmet Sinan
AU - Umut, Sema
AU - Unalan, Turgay
AU - Studnicka, Michael
AU - Dawes, Torkil
AU - Schirhofer, Lea
AU - Bateman, Eric
AU - Jithoo, Anamika
AU - Adams, Desiree
AU - Barnes, Edward
AU - Freeman, Jasper
AU - Hayes, Anton
AU - Hlengwa, Sipho
AU - Johannisen, Christine
AU - Koopman, Mariana
AU - Louw, Innocentia
AU - Ludick, Ina
AU - Olckers, Alta
AU - Ryck, Johanna
AU - Storbeck, Janita
AU - Gislason, Thorarinn
AU - Benedikdtsdottir, Bryndis
AU - Jörundsdottir, Kristin
AU - Gudmundsdottir, Lovisa
AU - Gudmundsdottir, Sigrun
AU - Gundmundsson, Gunnar
AU - Frey, Jakub
AU - Harat, Rafal
AU - Pajak, Andrzej
AU - Skucha, Wojciech
N1 - Publisher Copyright:
Copyright © ERS 2017. This version is distributed under the terms of the Creative Commons Attribution Licence 4.0.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - We studied the prevalence, burden and potential risk factors for chronic bronchitis symptoms in the Burden of Obstructive Lung Disease study. Representative population-based samples of adults aged ≥40 years were selected in participating sites. Participants completed questionnaires and spirometry. Chronic bronchitis symptoms were defined as chronic cough and phlegm on most days for ≥3 months each year for ≥2 years. Data from 24855 subjects from 33 sites in 29 countries were analysed. There were significant differences in the prevalence of self-reported symptoms meeting our definition of chronic bronchitis across sites, from 10.8% in Lexington (KY, USA), to 0% in Ile-Ife (Nigeria) and Blantyre (Malawi). Older age, less education, current smoking, occupational exposure to fumes, self-reported diagnosis of asthma or lung cancer and family history of chronic lung disease were all associated with increased risk of chronic bronchitis. Chronic bronchitis symptoms were associated with worse lung function, more dyspnoea, increased risk of respiratory exacerbations and reduced quality of life, independent of the presence of other lung diseases. The prevalence of chronic bronchitis symptoms varied widely across the studied sites. Chronic bronchitis symptoms were associated with significant burden both in individuals with chronic airflow obstruction and those with normal lung function.
AB - We studied the prevalence, burden and potential risk factors for chronic bronchitis symptoms in the Burden of Obstructive Lung Disease study. Representative population-based samples of adults aged ≥40 years were selected in participating sites. Participants completed questionnaires and spirometry. Chronic bronchitis symptoms were defined as chronic cough and phlegm on most days for ≥3 months each year for ≥2 years. Data from 24855 subjects from 33 sites in 29 countries were analysed. There were significant differences in the prevalence of self-reported symptoms meeting our definition of chronic bronchitis across sites, from 10.8% in Lexington (KY, USA), to 0% in Ile-Ife (Nigeria) and Blantyre (Malawi). Older age, less education, current smoking, occupational exposure to fumes, self-reported diagnosis of asthma or lung cancer and family history of chronic lung disease were all associated with increased risk of chronic bronchitis. Chronic bronchitis symptoms were associated with worse lung function, more dyspnoea, increased risk of respiratory exacerbations and reduced quality of life, independent of the presence of other lung diseases. The prevalence of chronic bronchitis symptoms varied widely across the studied sites. Chronic bronchitis symptoms were associated with significant burden both in individuals with chronic airflow obstruction and those with normal lung function.
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U2 - 10.1183/13993003.00621-2017
DO - 10.1183/13993003.00621-2017
M3 - Article
C2 - 29167298
AN - SCOPUS:85049432948
SN - 0903-1936
VL - 50
JO - European Respiratory Journal
JF - European Respiratory Journal
IS - 5
M1 - 1700621
ER -