Pressure effects on soft tissues monitored by changes in tissue optical properties

HanQun Shangguan, Scott A. Prahl, Steven Jacques, Lee W. Casperson, Kenton Gregory

Research output: Chapter in Book/Report/Conference proceedingConference contribution

39 Citations (Scopus)

Abstract

For pulsed laser tissue welding, an appropriate pressure needs to be applied to the tissues to achieve successful welds. In this study, we investigated the influences of pressure on in vitro optical properties of elastin biomaterial. The optical properties were measured as a function of pressure with a double integrating-sphere system. A He-Ne laser (633 nm) was used for all measurements. Each sample was sandwiched between microscope slides and then compressed with a spring-loaded apparatus. Transmittance and diffuse reflectance of each sample were measured under a pressure (0-1.5 kg/cm2 and then released to 0). Absorption and reduced scattering coefficients were calculated using the inverse doubling method from the measured transmittance and reflectance values. Results from this study demonstrated: 1) The overall transmittance increased while the reflectance decreased as the tissue thicknesses were reduced up to 72% and the tissue weights were decreased about 40%, 2) The absorption and scattering coefficients increased with increasing the pressure, and 3) The pressure effects on the tissue optical properties were irreversible. Possible mechanisms responsible for the changes in the tissue optical properties were also investigated by changing tissue thicknesses or weights (through dehydration). This study implies that changes in tissue thickness and water content are important factors that affect tissue optical properties in different ways.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsS.L. Jacques
Pages366-371
Number of pages6
Volume3254
DOIs
StatePublished - 1998
EventLaser-Tissue Interaction IX - San Jose, CA, United States
Duration: Jan 26 1998Jan 28 1998

Other

OtherLaser-Tissue Interaction IX
CountryUnited States
CitySan Jose, CA
Period1/26/981/28/98

Fingerprint

Pressure effects
pressure effects
Optical properties
Tissue
optical properties
transmittance
scattering coefficients
reflectance
Scattering
elastin
Elastin
Pulsed lasers
Dehydration
welding
chutes
Biomaterials
dehydration
Water content
moisture content
pulsed lasers

Keywords

  • Adding-doubling
  • Diffuse reflectance
  • Hydration
  • Transmittance

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Shangguan, H., Prahl, S. A., Jacques, S., Casperson, L. W., & Gregory, K. (1998). Pressure effects on soft tissues monitored by changes in tissue optical properties. In S. L. Jacques (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3254, pp. 366-371) https://doi.org/10.1117/12.308187

Pressure effects on soft tissues monitored by changes in tissue optical properties. / Shangguan, HanQun; Prahl, Scott A.; Jacques, Steven; Casperson, Lee W.; Gregory, Kenton.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / S.L. Jacques. Vol. 3254 1998. p. 366-371.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shangguan, H, Prahl, SA, Jacques, S, Casperson, LW & Gregory, K 1998, Pressure effects on soft tissues monitored by changes in tissue optical properties. in SL Jacques (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 3254, pp. 366-371, Laser-Tissue Interaction IX, San Jose, CA, United States, 1/26/98. https://doi.org/10.1117/12.308187
Shangguan H, Prahl SA, Jacques S, Casperson LW, Gregory K. Pressure effects on soft tissues monitored by changes in tissue optical properties. In Jacques SL, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3254. 1998. p. 366-371 https://doi.org/10.1117/12.308187
Shangguan, HanQun ; Prahl, Scott A. ; Jacques, Steven ; Casperson, Lee W. ; Gregory, Kenton. / Pressure effects on soft tissues monitored by changes in tissue optical properties. Proceedings of SPIE - The International Society for Optical Engineering. editor / S.L. Jacques. Vol. 3254 1998. pp. 366-371
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