Presence of lymphocyte membrane surface markers on 'small cells' in a pineal germinoma

Edward Neuwelt, R. G. Smith

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A 16-year-old boy was operated on via an occipital transtentorial craniotomy for a pineal tumor. Routine histological examination of the tissue revealed it to be a germinoma, as characterized by the presence of two cell populations: large cells and small, lymphoid-appearing cells. The cells were evaluated in a single-cell suspension for the presence of lymphocyte membrane surface markers; small cells exclusively were found to have such markers. A T-lymphocyte membrane marker was present in 81% of the small cells, whereas 15 to 18% of the small cells had a B-lymphocyte membrane marker.

Original languageEnglish (US)
Pages (from-to)133-136
Number of pages4
JournalAnnals of Neurology
Volume6
Issue number2
StatePublished - 1979
Externally publishedYes

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Germinoma
Lymphocytes
Membranes
Pinealoma
Craniotomy
Suspensions
B-Lymphocytes
T-Lymphocytes

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Presence of lymphocyte membrane surface markers on 'small cells' in a pineal germinoma. / Neuwelt, Edward; Smith, R. G.

In: Annals of Neurology, Vol. 6, No. 2, 1979, p. 133-136.

Research output: Contribution to journalArticle

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