Presence of lymphocyte membrane surface markers on 'small cells' in a pineal germinoma

Edward Neuwelt, R. G. Smith

Research output: Contribution to journalArticle

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A 16-year-old boy was operated on via an occipital transtentorial craniotomy for a pineal tumor. Routine histological examination of the tissue revealed it to be a germinoma, as characterized by the presence of two cell populations: large cells and small, lymphoid-appearing cells. The cells were evaluated in a single-cell suspension for the presence of lymphocyte membrane surface markers; small cells exclusively were found to have such markers. A T-lymphocyte membrane marker was present in 81% of the small cells, whereas 15 to 18% of the small cells had a B-lymphocyte membrane marker.

Original languageEnglish (US)
Pages (from-to)133-136
Number of pages4
JournalAnnals of Neurology
Issue number2
Publication statusPublished - 1979
Externally publishedYes


ASJC Scopus subject areas

  • Neuroscience(all)

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