Presence of lymphocyte membrane surface markers on “small cells” in a pineal germinoma

Edward A. Neuwelt, R. Graham Smith

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

A 16‐year‐old boy was operated on via an occipital transtentorial craniotomy for a pineal tumor. Routine histological examination of the tissue revealed it to be a germinoma, as characterized by the presence of two cell populations: large cells and small, lymphoidappearing cells. The cells were evaluated in a singlecell suspension for the peresence of lymphocyte membrane surface markers; small cells exclusively were found to have such markers; A T‐lymphocyte membrane marker was present in 81% of the small cells, whereas 15 to 18% of the small cells had a Blymphocyte membrane marker.

Original languageEnglish (US)
Pages (from-to)133-136
Number of pages4
JournalAnnals of Neurology
Volume6
Issue number2
DOIs
StatePublished - Aug 1979

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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