Preoperative radiation therapy for upper rectal cancer T3,T4/Nx: Selectivity essential

Sarah Popek, Vassiliki Liana Tsikitis, Lisa Hazard, Alfred M. Cohen

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

This review explores the current available literature regarding the role of neoadjuvant therapy for upper locally advanced rectal cancers (<10cm-15cm). Although there is a paucity of data evaluating the outcomes of preoperative chemoradiation for upper rectal cancers the authors suggest that T3N0 tumors will not likely benefit from radiation and that treatment of T4N0 should be individualized.

Original languageEnglish (US)
Pages (from-to)88-92
Number of pages5
JournalClinical Colorectal Cancer
Volume11
Issue number2
DOIs
StatePublished - Jun 2012
Externally publishedYes

Keywords

  • Neoadjuvant therapy
  • Rectal cancer
  • T3
  • T4Nx

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology

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