Preoperative radiation therapy for upper rectal cancer T3,T4/Nx: Selectivity essential

Sarah Popek, Vassiliki Liana Tsikitis, Lisa Hazard, Alfred M. Cohen

    Research output: Contribution to journalReview article

    8 Scopus citations

    Abstract

    This review explores the current available literature regarding the role of neoadjuvant therapy for upper locally advanced rectal cancers (<10cm-15cm). Although there is a paucity of data evaluating the outcomes of preoperative chemoradiation for upper rectal cancers the authors suggest that T3N0 tumors will not likely benefit from radiation and that treatment of T4N0 should be individualized.

    Original languageEnglish (US)
    Pages (from-to)88-92
    Number of pages5
    JournalClinical Colorectal Cancer
    Volume11
    Issue number2
    DOIs
    StatePublished - Jun 2012

    Keywords

    • Neoadjuvant therapy
    • Rectal cancer
    • T3
    • T4Nx

    ASJC Scopus subject areas

    • Oncology
    • Gastroenterology

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