Prenatal predictors of objectively measured appetite regulation in low-income toddlers and preschool-age children

Janne Heinonen, Heidi M. Weeks, Julie Sturza, Alison L. Miller, Julie C. Lumeng, Katherine W. Bauer

Research output: Contribution to journalArticle

Abstract

Background: Prenatal nutrition impacts offspring appetite regulation in animal models. However, evidence from humans is scarce. Objective: To determine associations between indicators of prenatal nutrition and appetite regulation among young children. Methods: Participants included 454 low-income mother/child dyads (mean child age = 45.2 months [SD = 9.7]). Children's appetite regulation was ascertained with the maternal-reported Child Eating Behavior Questionnaire and objectively assessed using the Eating in the Absence of Hunger protocol. Using hierarchical linear regression, we modelled child appetite regulation measures as a function of prenatal nutrition indicators (child birthweight z scores [BWz, BWz2]; maternal pre-pregnancy body mass index [BMI], gestational weight gain [GWG]), adjusted for sociodemographic characteristics. Results: Among girls, higher and lower birthweight were associated with greater energy consumed in the absence of hunger, primarily sweet foods, coeff (95% CI): BWz 0.17 (0.05, 0.28), BWz2 0.15 (0.04, 0.26), but not food responsiveness or food enjoyment. Higher birthweight was also associated with greater satiety responsiveness among girls. Among boys, birthweight was unrelated to measures of appetite regulation. Associations between maternal BMI and GWG and child appetite regulation were inconsistent. Conclusions: Among low-income girls, but not boys, indicators of adverse prenatal conditions were associated with poor objectively measured appetite regulation during early childhood.

Original languageEnglish (US)
Article numbere12554
JournalPediatric Obesity
DOIs
StatePublished - Jan 1 2019

Fingerprint

Appetite Regulation
Preschool Children
Mothers
Hunger
Food
Weight Gain
Body Mass Index
Child Behavior
Feeding Behavior
Linear Models
Animal Models
Eating
Pregnancy

Keywords

  • appetite regulation
  • birthweight
  • early childhood risk factors
  • maternal obesity

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Health Policy
  • Nutrition and Dietetics
  • Public Health, Environmental and Occupational Health

Cite this

Prenatal predictors of objectively measured appetite regulation in low-income toddlers and preschool-age children. / Heinonen, Janne; Weeks, Heidi M.; Sturza, Julie; Miller, Alison L.; Lumeng, Julie C.; Bauer, Katherine W.

In: Pediatric Obesity, 01.01.2019.

Research output: Contribution to journalArticle

Heinonen, Janne ; Weeks, Heidi M. ; Sturza, Julie ; Miller, Alison L. ; Lumeng, Julie C. ; Bauer, Katherine W. / Prenatal predictors of objectively measured appetite regulation in low-income toddlers and preschool-age children. In: Pediatric Obesity. 2019.
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