Preload dependency of left ventricular torsion the impact of normal saline infusion

Rory B. Weiner, Arthur E. Weyman, Abigail Khan, Jason S. Reingold, Annabel A. Chen-Tournoux, Marielle Scherrer-Crosbie, Michael H. Picard, Thomas J. Wang, Aaron L. Baggish

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Background - Left ventricular (LV) rotation results from contraction of obliquely oriented myocardial fibers. The net difference between systolic apical counterclockwise rotation and basal clockwise rotation is left ventricular torsion (LVT). Although LVT is altered in various cardiac diseases, determinants of LVT are incompletely understood. Methods and Results-LV end-diastolic volume, LV apical and basal rotation, peak systolic LVT, and peak early diastolic untwisting rate were measured by speckle-tracking echocardiography in healthy subjects (n=8) before and after infusion of a weight-based normal saline bolus (2.1±0.3 L). Saline infusion led to a significant increase in end-diastolic LV internal diameter (45.9±3.7 versus 47.6±4.2 mm; P=0.002) and LV end-diastolic volume (90.0±21.6 versus 98.3±19.6 mL; P=0.01). Stroke volume (51.3±10.9 versus 63.0±15.5 mL; P=0.003) and cardiac output (3.4±0.8 versus 4.4±1.5 L/min; P=0.007) increased, whereas there was no change in heart rate and blood pressure. There was a significant increase in the magnitude of peak systolic apical rotation (7.5±2.4° versus 10.5±2.8°; P

Original languageEnglish (US)
Pages (from-to)672-678
Number of pages7
JournalCirculation: Cardiovascular Imaging
Volume3
Issue number6
DOIs
StatePublished - Nov 2010
Externally publishedYes

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Stroke Volume
Cardiac Output
Echocardiography
Heart Diseases
Healthy Volunteers
Heart Rate
Blood Pressure
Weights and Measures

Keywords

  • Cardiac volume
  • Echocardiography
  • Mechanics
  • Torsion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Weiner, R. B., Weyman, A. E., Khan, A., Reingold, J. S., Chen-Tournoux, A. A., Scherrer-Crosbie, M., ... Baggish, A. L. (2010). Preload dependency of left ventricular torsion the impact of normal saline infusion. Circulation: Cardiovascular Imaging, 3(6), 672-678. https://doi.org/10.1161/CIRCIMAGING.109.932921

Preload dependency of left ventricular torsion the impact of normal saline infusion. / Weiner, Rory B.; Weyman, Arthur E.; Khan, Abigail; Reingold, Jason S.; Chen-Tournoux, Annabel A.; Scherrer-Crosbie, Marielle; Picard, Michael H.; Wang, Thomas J.; Baggish, Aaron L.

In: Circulation: Cardiovascular Imaging, Vol. 3, No. 6, 11.2010, p. 672-678.

Research output: Contribution to journalArticle

Weiner, RB, Weyman, AE, Khan, A, Reingold, JS, Chen-Tournoux, AA, Scherrer-Crosbie, M, Picard, MH, Wang, TJ & Baggish, AL 2010, 'Preload dependency of left ventricular torsion the impact of normal saline infusion', Circulation: Cardiovascular Imaging, vol. 3, no. 6, pp. 672-678. https://doi.org/10.1161/CIRCIMAGING.109.932921
Weiner, Rory B. ; Weyman, Arthur E. ; Khan, Abigail ; Reingold, Jason S. ; Chen-Tournoux, Annabel A. ; Scherrer-Crosbie, Marielle ; Picard, Michael H. ; Wang, Thomas J. ; Baggish, Aaron L. / Preload dependency of left ventricular torsion the impact of normal saline infusion. In: Circulation: Cardiovascular Imaging. 2010 ; Vol. 3, No. 6. pp. 672-678.
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