Preliminary studies of a simultaneous PET/MRI scanner based on the RatCAP small animal tomograph

D. Schlyer, P. Vaska, D. Tomasi, C. Woody, S. Solis-Najera, S. Southekal, W. Rooney, J. F. Pratte, S. Junnarkar, S. Stoll, M. Purschke, S. J. Park, Z. Master, S. H. Maramraju, S. Krishnamoorthy, A. Kriplani, W. Schiffer, P. O'Connor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

We are developing a scanner that will allow the simultaneous acquisition of high resolution anatomical data using Magnetic Resonance Imaging (MRI) and quantitative physiological data using Positron Emission Tomography (PET). The approach is based on the technology used for the RatCAP conscious small animal PET tomograph which utilizes block detectors consisting of pixelated arrays of LSO crystals read out with matching arrays of avalanche photodiodes (APDs) and a custom-designed ASIC. A version of the detector is being developed that will be constructed out of all non-magnetic materials that can be operated inside the MRI field. We have demonstrated that the PET detector works inside the MRI field using 511 keV gamma rays, and have obtained MRI images with various detector components that show minimal distortion in the MRI image. We plan to improve on the image quality in the future using completely non-magnetic components and by tuning the MRI pulse sequences. The combined result will be a highly compact, low mass PET scanner that can operate inside an MRI magnet without distorting the MRI image, and can be retrofitted into existing MRI instruments.

Original languageEnglish (US)
Title of host publication2006 IEEE Nuclear Science Symposium - Conference Record
Pages2340-2344
Number of pages5
DOIs
StatePublished - Dec 1 2007
Event2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD - San Diego, CA, United States
Duration: Oct 29 2006Nov 4 2006

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume4
ISSN (Print)1095-7863

Other

Other2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD
CountryUnited States
CitySan Diego, CA
Period10/29/0611/4/06

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ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

Cite this

Schlyer, D., Vaska, P., Tomasi, D., Woody, C., Solis-Najera, S., Southekal, S., Rooney, W., Pratte, J. F., Junnarkar, S., Stoll, S., Purschke, M., Park, S. J., Master, Z., Maramraju, S. H., Krishnamoorthy, S., Kriplani, A., Schiffer, W., & O'Connor, P. (2007). Preliminary studies of a simultaneous PET/MRI scanner based on the RatCAP small animal tomograph. In 2006 IEEE Nuclear Science Symposium - Conference Record (pp. 2340-2344). [4179497] (IEEE Nuclear Science Symposium Conference Record; Vol. 4). https://doi.org/10.1109/NSSMIC.2006.354383