Predictors of pouchitis after ileal pouch-anal anastomosis: A retrospective review

Katherine Mary Hoda, Judith (Judy) Collins, Kandice Knigge, Karen Deveney

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

PURPOSE: The primary end point of this study was to determine the risk factors that predict chronic pouchitis in those patients having ileal pouch-anal anastomosis. METHODS: A total of 237 patients with ulcerative colitis and undergoing ileal pouch-anal anastomosis by one surgeon at Oregon Health & Science University from 1993 to 2003 were evaluated. Data were gathered via retrospective chart reviews and by a questionnaire administered by telephone in 2004. Patients were excluded if there was less than one-year follow-up documented in the chart or they could not be contacted by telephone (n=62), postoperative diagnosis of Crohn's disease (n=3), failed ileoanal procedure (n=1), and one-stage ileal pouch-anal anastomosis (n=3), leaving 167 patients for evaluation. Patients were defined as having chronic pouchitis (>3 episodes of pouchitis) or no pouchitis (≤ 3 episodes of pouchitis). Potential risk factors included number of operations used to perform ileal pouch-anal anastomosis, fulminant ulcerative colitis with two-stage operation, duration of diverting ileostomy after pouch formation, primary sclerosing cholangitis, other extraintestinal manifestations of ulcerative colitis, preoperative liver function tests, duration of ulcerative colitis, and the occurrence of postoperative complications. Initial univariate analysis was performed on all risk factors. Multivariate analysis was performed on all univariate risk factors with P values

Original languageEnglish (US)
Pages (from-to)554-560
Number of pages7
JournalDiseases of the Colon and Rectum
Volume51
Issue number5
DOIs
StatePublished - May 2008

Fingerprint

Pouchitis
Colonic Pouches
Ulcerative Colitis
Telephone
Sclerosing Cholangitis
Ileostomy
Liver Function Tests
Crohn Disease
Multivariate Analysis
Health

Keywords

  • Ileal pouch-anal anastomosis
  • Pouchitis
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Predictors of pouchitis after ileal pouch-anal anastomosis : A retrospective review. / Hoda, Katherine Mary; Collins, Judith (Judy); Knigge, Kandice; Deveney, Karen.

In: Diseases of the Colon and Rectum, Vol. 51, No. 5, 05.2008, p. 554-560.

Research output: Contribution to journalArticle

@article{8aaca4f0f11640c1a0d83bc87c742e3a,
title = "Predictors of pouchitis after ileal pouch-anal anastomosis: A retrospective review",
abstract = "PURPOSE: The primary end point of this study was to determine the risk factors that predict chronic pouchitis in those patients having ileal pouch-anal anastomosis. METHODS: A total of 237 patients with ulcerative colitis and undergoing ileal pouch-anal anastomosis by one surgeon at Oregon Health & Science University from 1993 to 2003 were evaluated. Data were gathered via retrospective chart reviews and by a questionnaire administered by telephone in 2004. Patients were excluded if there was less than one-year follow-up documented in the chart or they could not be contacted by telephone (n=62), postoperative diagnosis of Crohn's disease (n=3), failed ileoanal procedure (n=1), and one-stage ileal pouch-anal anastomosis (n=3), leaving 167 patients for evaluation. Patients were defined as having chronic pouchitis (>3 episodes of pouchitis) or no pouchitis (≤ 3 episodes of pouchitis). Potential risk factors included number of operations used to perform ileal pouch-anal anastomosis, fulminant ulcerative colitis with two-stage operation, duration of diverting ileostomy after pouch formation, primary sclerosing cholangitis, other extraintestinal manifestations of ulcerative colitis, preoperative liver function tests, duration of ulcerative colitis, and the occurrence of postoperative complications. Initial univariate analysis was performed on all risk factors. Multivariate analysis was performed on all univariate risk factors with P values",
keywords = "Ileal pouch-anal anastomosis, Pouchitis, Ulcerative colitis",
author = "Hoda, {Katherine Mary} and Collins, {Judith (Judy)} and Kandice Knigge and Karen Deveney",
year = "2008",
month = "5",
doi = "10.1007/s10350-008-9194-7",
language = "English (US)",
volume = "51",
pages = "554--560",
journal = "Diseases of the Colon and Rectum",
issn = "0012-3706",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Predictors of pouchitis after ileal pouch-anal anastomosis

T2 - A retrospective review

AU - Hoda, Katherine Mary

AU - Collins, Judith (Judy)

AU - Knigge, Kandice

AU - Deveney, Karen

PY - 2008/5

Y1 - 2008/5

N2 - PURPOSE: The primary end point of this study was to determine the risk factors that predict chronic pouchitis in those patients having ileal pouch-anal anastomosis. METHODS: A total of 237 patients with ulcerative colitis and undergoing ileal pouch-anal anastomosis by one surgeon at Oregon Health & Science University from 1993 to 2003 were evaluated. Data were gathered via retrospective chart reviews and by a questionnaire administered by telephone in 2004. Patients were excluded if there was less than one-year follow-up documented in the chart or they could not be contacted by telephone (n=62), postoperative diagnosis of Crohn's disease (n=3), failed ileoanal procedure (n=1), and one-stage ileal pouch-anal anastomosis (n=3), leaving 167 patients for evaluation. Patients were defined as having chronic pouchitis (>3 episodes of pouchitis) or no pouchitis (≤ 3 episodes of pouchitis). Potential risk factors included number of operations used to perform ileal pouch-anal anastomosis, fulminant ulcerative colitis with two-stage operation, duration of diverting ileostomy after pouch formation, primary sclerosing cholangitis, other extraintestinal manifestations of ulcerative colitis, preoperative liver function tests, duration of ulcerative colitis, and the occurrence of postoperative complications. Initial univariate analysis was performed on all risk factors. Multivariate analysis was performed on all univariate risk factors with P values

AB - PURPOSE: The primary end point of this study was to determine the risk factors that predict chronic pouchitis in those patients having ileal pouch-anal anastomosis. METHODS: A total of 237 patients with ulcerative colitis and undergoing ileal pouch-anal anastomosis by one surgeon at Oregon Health & Science University from 1993 to 2003 were evaluated. Data were gathered via retrospective chart reviews and by a questionnaire administered by telephone in 2004. Patients were excluded if there was less than one-year follow-up documented in the chart or they could not be contacted by telephone (n=62), postoperative diagnosis of Crohn's disease (n=3), failed ileoanal procedure (n=1), and one-stage ileal pouch-anal anastomosis (n=3), leaving 167 patients for evaluation. Patients were defined as having chronic pouchitis (>3 episodes of pouchitis) or no pouchitis (≤ 3 episodes of pouchitis). Potential risk factors included number of operations used to perform ileal pouch-anal anastomosis, fulminant ulcerative colitis with two-stage operation, duration of diverting ileostomy after pouch formation, primary sclerosing cholangitis, other extraintestinal manifestations of ulcerative colitis, preoperative liver function tests, duration of ulcerative colitis, and the occurrence of postoperative complications. Initial univariate analysis was performed on all risk factors. Multivariate analysis was performed on all univariate risk factors with P values

KW - Ileal pouch-anal anastomosis

KW - Pouchitis

KW - Ulcerative colitis

UR - http://www.scopus.com/inward/record.url?scp=43049147568&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43049147568&partnerID=8YFLogxK

U2 - 10.1007/s10350-008-9194-7

DO - 10.1007/s10350-008-9194-7

M3 - Article

C2 - 18266037

AN - SCOPUS:43049147568

VL - 51

SP - 554

EP - 560

JO - Diseases of the Colon and Rectum

JF - Diseases of the Colon and Rectum

SN - 0012-3706

IS - 5

ER -