Predictors of long-term success after microvascular decompression for trigeminal neuralgia: Clinical article

Jonathan P. Miller, Stephen T. Magill, Feridun Acar, Kim Burchiel

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Object. Microvascular decompression (MVD) is an effective treatment for trigeminal neuralgia (TN). However, many patients do not experience complete pain relief, and relapse can occur even after an initial excellent result. This study was designed to identify characteristics associated with improved long-term outcome after MVD. Methods. One hundred seventy-nine consecutive patients who had undergone MVD for TN at the authors' institution were contacted, and 95 were enrolled in the study. Patients provided information about preoperative pain characteristics including preponderance of shock-like (Type 1 TN) or constant (Type 2 TN) pain, preoperative duration, trigger points, anticonvulsant therapy response, memorable onset, and pain-free intervals. Three groups were defined based on outcome: 1) excellent, pain relief without medication; 2) good, mild or intermittent pain controlled with low-dose medication; and 3) poor, severe persistent pain or need for additional surgical treatment. Results. Type of TN pain (Type 1 TN vs Type 2 TN) was the only significant predictor of outcome after MVD. Results were excellent, good, and poor for Type 1 TN versus Type 2 TN patients in 60 versus 25%, 24 versus 39%, and 16 versus 36%, respectively. Among patients with each TN type, there was a significant trend toward better outcome with greater proportional contribution of Type 1 TN (lancinating) symptoms (p <0.05). Conclusions. Pain relief after MVD is strongly correlated with the lancinating pain component, and therefore type of TN pain is the best predictor of long-term outcome after MVD. Application of this information should be helpful in the selection of TN patients likely to benefit from MVD.

Original languageEnglish (US)
Pages (from-to)620-626
Number of pages7
JournalJournal of Neurosurgery
Volume110
Issue number4
DOIs
StatePublished - Apr 2009

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Microvascular Decompression Surgery
Trigeminal Neuralgia
Pain
Trigger Points
Anticonvulsants

Keywords

  • Facial pain
  • Microvascular decompression
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Predictors of long-term success after microvascular decompression for trigeminal neuralgia : Clinical article. / Miller, Jonathan P.; Magill, Stephen T.; Acar, Feridun; Burchiel, Kim.

In: Journal of Neurosurgery, Vol. 110, No. 4, 04.2009, p. 620-626.

Research output: Contribution to journalArticle

Miller, Jonathan P. ; Magill, Stephen T. ; Acar, Feridun ; Burchiel, Kim. / Predictors of long-term success after microvascular decompression for trigeminal neuralgia : Clinical article. In: Journal of Neurosurgery. 2009 ; Vol. 110, No. 4. pp. 620-626.
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