A monoclonal antibody was generated, against early neural crest-derived cells, which recognizes an epitope present on a novel intermediate filament-associated protein. This protein has been named NAPA-73 and is expressed by progenitor cells of the nervous system and heart. Biochemical and ultrastructural studies indicate that this protein associates with bundles of intermediate filaments and therefore may play a role in the determination of cell shape.
|Original language||English (US)|
|Number of pages||11|
|Journal||Annals of the New York Academy of Sciences|
|Publication status||Published - 1990|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)