Practice patterns in the management of fungal corneal ulcers

Allison Loh, Kevin Hong, Salena Lee, Mark Mannis, Nisha R. Acharya

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

PURPOSE: The purpose of this study was to determine the practice patterns of ophthalmologists in the management of fungal corneal ulcers. METHODS: In December 2007, a survey of 13 questions addressing the actual and preferred treatment of fungal ulcers was sent to the kera-net e-mail listserv facilitated by the Cornea Society. RESULTS: Ninety-two respondents from North America, South America, Asia, Europe, and Australia participated by completing the electronic questionnaire. Natamycin was the most commonly used topical treatment for ulcers caused by filamentous fungi (96%) followed by amphotericin (75%) and voriconazole (63%). However, voriconazole was most often listed as the preferred topical treatment in an ideal world (79%) compared with 55% for natamycin. Approximately half of the respondents use combination topical therapy (56%) and the remainder monotherapy. The majority of respondents rescrape the epithelium at some time during the course of treatment, but the frequency of rescraping varied among the different topical treatments. The most common reasons cited for not using their preferred treatment were cost and a desire for further evidence to support preferred treatment. CONCLUSION: There appears to be significant variation in the management of fungal corneal ulcers. Although natamycin was the most commonly used treatment for ulcers caused by filamentous fungi, voriconazole was the most preferred as the ideal treatment. These results highlight the need for more evidence regarding the efficacy of the newer topical antifungals.

Original languageEnglish (US)
Pages (from-to)856-859
Number of pages4
JournalCornea
Volume28
Issue number8
DOIs
StatePublished - Sep 2009
Externally publishedYes

Fingerprint

Corneal Ulcer
Natamycin
Ulcer
Therapeutics
Fungi
South America
Postal Service
Amphotericin B
North America
Health Care Costs
Cornea
Epithelium
Surveys and Questionnaires

Keywords

  • Antifungals
  • Fungal corneal ulcers
  • Management
  • Practice patterns
  • Voriconazole

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Loh, A., Hong, K., Lee, S., Mannis, M., & Acharya, N. R. (2009). Practice patterns in the management of fungal corneal ulcers. Cornea, 28(8), 856-859. https://doi.org/10.1097/ICO.0b013e318199fa77

Practice patterns in the management of fungal corneal ulcers. / Loh, Allison; Hong, Kevin; Lee, Salena; Mannis, Mark; Acharya, Nisha R.

In: Cornea, Vol. 28, No. 8, 09.2009, p. 856-859.

Research output: Contribution to journalArticle

Loh, A, Hong, K, Lee, S, Mannis, M & Acharya, NR 2009, 'Practice patterns in the management of fungal corneal ulcers', Cornea, vol. 28, no. 8, pp. 856-859. https://doi.org/10.1097/ICO.0b013e318199fa77
Loh, Allison ; Hong, Kevin ; Lee, Salena ; Mannis, Mark ; Acharya, Nisha R. / Practice patterns in the management of fungal corneal ulcers. In: Cornea. 2009 ; Vol. 28, No. 8. pp. 856-859.
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